Entity Details

Primary name RAC3
Entity type gene
Source Source Link

Details

PrimaryID5881
RefseqGene
SymbolRAC3
NameRac family small GTPase 3
Chromosome17
Location17q25.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsRAC3_HUMAN

GO terms

Show/Hide Table
GOName
GO:0003924 GTPase activity
GO:0003925 G protein activity
GO:0005525 GTP binding
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005938 cell cortex
GO:0007015 actin filament organization
GO:0007163 establishment or maintenance of cell polarity
GO:0007264 small GTPase mediated signal transduction
GO:0008360 regulation of cell shape
GO:0012505 endomembrane system
GO:0014041 regulation of neuron maturation
GO:0016055 Wnt signaling pathway
GO:0019901 protein kinase binding
GO:0021894 cerebral cortex GABAergic interneuron development
GO:0030027 lamellipodium
GO:0030031 cell projection assembly
GO:0030036 actin cytoskeleton organization
GO:0030426 growth cone
GO:0030865 cortical cytoskeleton organization
GO:0031175 neuron projection development
GO:0031410 cytoplasmic vesicle
GO:0031941 filamentous actin
GO:0032956 regulation of actin cytoskeleton organization
GO:0033630 positive regulation of cell adhesion mediated by integrin
GO:0035556 intracellular signal transduction
GO:0042995 cell projection
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043231 intracellular membrane-bounded organelle
GO:0045202 synapse
GO:0048306 calcium-dependent protein binding
GO:0048471 perinuclear region of cytoplasm
GO:0048873 homeostasis of number of cells within a tissue
GO:0050885 neuromuscular process controlling balance
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0051932 synaptic transmission, GABAergic
GO:0070062 extracellular exosome
GO:0071944 cell periphery
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading

Diseases

Show/Hide Table
Disease IDSourceNameDescription
618577 OMIMNeurodevelopmental disorder with structural brain anomalies and dysmorphic facies (NEDBAF)An autosomal dominant neurodevelopmental disorder characterized by global developmental delay, severe intellectual disability, poor language, seizures, dysmorphic features, and thin corpus callosum. The disease is caused by variants affecting the gene represented in this entry.