Entity Details

Primary name CLPP
Entity type gene
Source Source Link

Details

PrimaryID8192
RefseqGeneNG_033887
SymbolCLPP
Namecaseinolytic mitochondrial matrix peptidase proteolytic subunit
Chromosome19
Location19p13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-09-16
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsCLPP_HUMAN

GO terms

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GOName
GO:0004175 endopeptidase activity
GO:0004176 ATP-dependent peptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0006515 protein quality control for misfolded or incompletely synthesized proteins
GO:0008233 peptidase activity
GO:0009368 endopeptidase Clp complex
GO:0033619 membrane protein proteolysis
GO:0042802 identical protein binding
GO:0051117 ATPase binding
GO:0051603 proteolysis involved in cellular protein catabolic process

Diseases

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Interactions

320 interactions

InteractorPartnerSourcesPublicationsLink
CLPPCLPXBioGRID, HPRD, IntAct11923310 26058080 details
CLPPPLSCR4BioGRID, IntAct32296183 details
CLPPDTX2BioGRID, IntAct32296183 details
CLPPEFEMP2BioGRID, IntAct32296183 details
CLPPCLPPBioGRID, DIP, HPRD16115876 20637416 31056398 details
CLPPPPP2CABioGRID, IntAct32296183 details
CLPPAPPIntAct32814053 details
CLPPTARDBPIntAct32814053 details
CLPPRBPMSBioGRID, IntAct32296183 details
CLPPSNCABioGRID, IntAct30877431 32814053 details
CLPPP4HA3BioGRID, IntAct32296183 details
CLPPKRTAP10-1BioGRID32296183 details
CLPPCHCHD3BioGRID30877431 31056398 details
CLPPTNPO3BioGRID, IntAct32296183 details
CLPPPSMB1BioGRID, IntAct32296183 details
CLPPNUTF2BioGRID, IntAct32296183 details
CLPPGRNBioGRID, IntAct32296183 details
CLPPEFEMP1BioGRID, IntAct32296183 details
CLPPABI2BioGRID, IntAct32296183 details
CLPPC14orf119BioGRID, IntAct32296183 details
CLPPTRIM54BioGRID, IntAct31391242 details
CLPPDNM2IntAct32814053 details
CLPPWFS1IntAct32814053 details
CLPPGDAP1IntAct32814053 details
CLPPJPH3IntAct32814053 details
CLPPHTTIntAct32814053 details
CLPPATXN3IntAct32814053 details
CLPPGH1IntAct17353931 details
CLPPRAB5IFIntAct17353931 details
CLPPHLA-BIntAct17353931 details
CLPPRBM47BioGRID29395067 details
CLPPSAP18IntAct17353931 details
CLPPGRSF1BioGRID29395067 31056398 details
CLPPACO2BioGRID, IntAct26058080 31056398 details
CLPPTSTBioGRID, IntAct26058080 31056398 details
CLPPATP5MKBioGRID, IntAct26058080 details
CLPPMRRFBioGRID, IntAct26058080 31056398 details
CLPPNDUFAF1BioGRID, IntAct26058080 31056398 details
CLPPCOX7CBioGRID, IntAct26058080 details
CLPPGLUD2BioGRID, IntAct26058080 details
CLPPCOQ3BioGRID, IntAct26058080 details
CLPPMTRF1BioGRID, IntAct26058080 31056398 32877691 details
CLPPPOLG2BioGRID, IntAct26058080 31056398 details
CLPPGCDHBioGRID, IntAct26058080 31056398 details
CLPPPDK3BioGRID, IntAct26058080 31056398 details
CLPPUQCR10BioGRID, IntAct26058080 details
CLPPNDUFA4BioGRID, IntAct26058080 details
CLPPCBR4BioGRID, IntAct26058080 details
CLPPALAS1BioGRID, IntAct26058080 details
CLPPTMLHEBioGRID, IntAct26058080 details
CLPPCDS2BioGRID, IntAct26058080 details
CLPPCOX6A1BioGRID, IntAct26058080 details
CLPPFDX1BioGRID, IntAct26058080 details
CLPPHSD17B4BioGRID, IntAct26058080 details
CLPPACSS1BioGRID, IntAct26058080 31056398 details
CLPPATP8BioGRID, IntAct26058080 details
CLPPNARS2BioGRID, IntAct26058080 31056398 details
CLPPPMPCBBioGRID, IntAct26058080 details
CLPPND1BioGRID, IntAct26058080 details
CLPPACADSBBioGRID, IntAct26058080 31056398 details
CLPPACADMBioGRID, IntAct26058080 31056398 details
CLPPWARS2BioGRID, IntAct26058080 31056398 details
CLPPTFAMBioGRID, IntAct26058080 31056398 details
CLPPSDHCBioGRID, IntAct26058080 details
CLPPNIPSNAP1BioGRID, IntAct26058080 31056398 details
CLPPFECHBioGRID, IntAct26058080 31056398 details
CLPPSSBP1BioGRID, IntAct26058080 31056398 32877691 details
CLPPGSTK1BioGRID, IntAct26058080 details
CLPPOXCT1BioGRID, IntAct26058080 31056398 details
CLPPCOX5BBioGRID, IntAct26058080 31056398 details
CLPPAK3BioGRID, IntAct26058080 31056398 details
CLPPPOLDIP2BioGRID, IntAct26058080 details
CLPPIDH3BBioGRID, IntAct26058080 details
CLPPAK4IntAct26058080 details
CLPPQRSL1BioGRID, IntAct26058080 31056398 details
CLPPCOX5ABioGRID, IntAct26058080 31056398 details
CLPPNFS1BioGRID, IntAct26058080 31056398 details
CLPPCARS2BioGRID, IntAct26058080 31056398 details
CLPPALDH4A1BioGRID, IntAct26058080 31056398 details
CLPPCSBioGRID, IntAct26058080 32877691 34079125 details
CLPPSDHABioGRID, IntAct26058080 31056398 details
CLPPSNRNP27BioGRID, IntAct28514442 details
CLPPMRPL12BioGRID, IntAct28514442 31056398 details
CLPPMRPS30BioGRID, IntAct26186194 28514442 details
CLPPECSITBioGRID, IntAct26186194 28514442 31056398 details
CLPPARNTL2BioGRID, IntAct28514442 details
CLPPZNF133BioGRID, IntAct28514442 details
CLPPNDUFA10BioGRID, IntAct26186194 28514442 details
CLPPUSP47BioGRID, IntAct28514442 details
CLPPTRIM43BioGRID, IntAct28514442 details
CLPPFBXO17BioGRID, IntAct26186194 28514442 details
CLPPYBEYBioGRID, IntAct28514442 details
CLPPFOXRED1BioGRID, IntAct28514442 31056398 details
CLPPFDPSBioGRID, IntAct28514442 details
CLPPPPA2BioGRID, IntAct26186194 28514442 31056398 details
CLPPIMPDH1BioGRID, IntAct28514442 details
CLPPAIFM1BioGRID, IntAct29568061 31056398 details
CLPPMTG2BioGRID, IntAct28514442 32877691 details
CLPPHSPD1BioGRID, IntAct29568061 details
CLPPARNT2BioGRID, IntAct28514442 details
CLPPCOX14BioGRID, IntAct29568061 details
CLPPUQCC1BioGRID, IntAct28514442 details
CLPPMGST3IntAct29568061 details
CLPPAURKAIP1BioGRID, IntAct29568061 details
CLPPTRMT61BBioGRID, IntAct29568061 details
CLPPNEURL4IntAct29426014 details
CLPPNGEFBioGRID, IntAct32203420 details
CLPPCHCHD2IntAct27499296 details
CLPPSCO1BioGRID, IntAct29568061 details
CLPPNDUFS3IntAct27499296 details
CLPPOATBioGRID31536960 details
CLPPEGFRBioGRID24797263 details
CLPPSPATA20IntAct27499296 details
CLPPPAICSBioGRID31536960 details
CLPPMRM1BioGRID29568061 details
CLPPTRUB2IntAct27499296 details
CLPPIMMP1LBioGRID31617661 details
CLPPPDK1BioGRID, IntAct29568061 details
CLPPLDHBBioGRID31536960 details
CLPPCOL6A1BioGRID31536960 details
CLPPACAD9BioGRID31056398 32877691 details
CLPPSHMT2BioGRID31056398 31536960 details
CLPPPYCR2BioGRID31056398 31536960 details
CLPPAUHBioGRID32877691 details
CLPPGAP43BioGRID31536960 details
CLPPPYCR1BioGRID31056398 31536960 details
CLPPGATD3BioGRID32877691 details
CLPPLRRK2IntAct31046837 details
CLPPCOL11A1BioGRID31536960 details
CLPPSLC2A3BioGRID31536960 details
CLPPLRPPRCBioGRID32877691 details
CLPPFBXW11BioGRID25900982 details
CLPPHADHABioGRID31536960 details
CLPPESR1BioGRID23403292 details
CLPPMETTL17BioGRID31056398 32877691 details
CLPPME2BioGRID31536960 details
CLPPPMPCABioGRID31056398 32877691 details
CLPPHSPA4BioGRID31536960 details
CLPPC1QBPBioGRID32877691 details
CLPPTSFMBioGRID32877691 details
CLPPPLEKHA4BioGRID31091453 details
CLPPFASTKD5BioGRID31056398 32877691 details
CLPPBCS1LBioGRID31056398 details
CLPPPRDX4BioGRID31536960 details
CLPPMTRES1BioGRID32877691 details
CLPPCOX4I1BioGRID31056398 34079125 details
CLPPRCN2BioGRID31536960 details
CLPPGFM1BioGRID31056398 32877691 details
CLPPMCUR1BioGRID32877691 details
CLPPMRPS12BioGRID32877691 details
CLPPMTIF2BioGRID31056398 32877691 details
CLPPGLSBioGRID31056398 details
CLPPMRPS26BioGRID31056398 32877691 details
CLPPEXD2BioGRID32877691 details
CLPPIDI1BioGRID31056398 details
CLPPMDH2BioGRID31056398 32877691 details
CLPPABCB7BioGRID31056398 details
CLPPNDUFA2BioGRID31056398 details
CLPPACADVLBioGRID31056398 details
CLPPNDUFA7BioGRID31056398 details
CLPPMRPL11BioGRID32877691 details
CLPPARG2BioGRID31056398 details
CLPPACAT1BioGRID31056398 details
CLPPNDUFS8BioGRID31056398 details
CLPPCPOXBioGRID31056398 details
CLPPBCKDHABioGRID31056398 details
CLPPNME4BioGRID31056398 details
CLPPTUFMBioGRID32877691 details
CLPPNIPSNAP2BioGRID31056398 details
CLPPETFBBioGRID31056398 details
CLPPPCK2BioGRID31056398 details
CLPPABATBioGRID31056398 details
CLPPIDEBioGRID31056398 details
CLPPGLUD1BioGRID31056398 details
CLPPGATBBioGRID26058080 31056398 details
CLPPALDH2BioGRID31056398 details
CLPPIDH3ABioGRID31056398 details
CLPPHADHBioGRID31056398 details
CLPPPRKCABioGRID31056398 details
CLPPBCKDHBBioGRID31056398 details
CLPPNDUFS4BioGRID31056398 details
CLPPHSPA1LBioGRID31056398 details
CLPPMRPL19BioGRID31056398 details
CLPPCRATBioGRID31056398 details
CLPPNDUFV2BioGRID31056398 details
CLPPHSPE1BioGRID31056398 details
CLPPPPIFBioGRID31056398 details
CLPPECHS1BioGRID31056398 details
CLPPRPS15ABioGRID31056398 details
CLPPLETM1BioGRID31056398 details
CLPPACAA2BioGRID31056398 details
CLPPPDIA3BioGRID31056398 details
CLPPSDHBBioGRID31056398 details
CLPPALDH6A1BioGRID31056398 details
CLPPTIMM44BioGRID31056398 details
CLPPHSD17B10BioGRID31056398 details
CLPPSUPV3L1BioGRID31056398 details
CLPPMPSTBioGRID31056398 details
CLPPAFG3L2BioGRID31056398 details
CLPPNUDT1BioGRID31056398 details
CLPPUQCRBBioGRID31056398 details
CLPPNDUFS2BioGRID31056398 details
CLPPVWA8BioGRID31056398 details
CLPPNDUFA6BioGRID31056398 details
CLPPSUCLG1BioGRID31056398 details
CLPPNDUFS6BioGRID31056398 details
CLPPHARS2BioGRID31056398 details
CLPPNDUFV3BioGRID31056398 details
CLPPPITRM1BioGRID31056398 details
CLPPPOLRMTBioGRID31056398 details
CLPPABCB10BioGRID31056398 details
CLPPOGDHBioGRID31056398 details
CLPPMTHFD2BioGRID31056398 details
CLPPSUCLG2BioGRID31056398 details
CLPPERAL1BioGRID31056398 details
CLPPOXA1LBioGRID31056398 details
CLPPFASTKD2BioGRID31056398 details
CLPPSUCLA2BioGRID31056398 details
CLPPMRPS28BioGRID31056398 details
CLPPMTHFD1LBioGRID31056398 details
CLPPTBRG4BioGRID31056398 details
CLPPCOQ6BioGRID31056398 details
CLPPPIN1BioGRID31056398 details
CLPPMRPS7BioGRID31056398 details
CLPPDHRS4BioGRID31056398 details
CLPPGLRX5BioGRID31056398 details
CLPPPOLGBioGRID31056398 details
CLPPMRPL48BioGRID31056398 details
CLPPCLIC4BioGRID31056398 details
CLPPMRPS17BioGRID31056398 details
CLPPHSD17B8BioGRID31056398 details
CLPPNDUFAF7BioGRID31056398 details
CLPPNDUFAF4BioGRID31056398 details
CLPPCDK5RAP1BioGRID31056398 details
CLPPSLC27A2BioGRID31056398 details
CLPPLYRM4BioGRID31056398 details
CLPPMRPS16BioGRID31056398 details
CLPPMRM3BioGRID31056398 details
CLPPLARS2BioGRID31056398 details
CLPPGUF1BioGRID31056398 details
CLPPDHTKD1BioGRID31056398 details
CLPPSDHAF3BioGRID31056398 details
CLPPNDUFAF3BioGRID31056398 details
CLPPMRPS25BioGRID31056398 details
CLPPNDUFA12BioGRID31056398 details
CLPPMRPL14BioGRID31056398 details
CLPPHIBCHBioGRID31056398 details
CLPPATPAF1BioGRID31056398 details
CLPPMRPL47BioGRID31056398 details
CLPPMRPS24BioGRID31056398 details
CLPPMRPL46BioGRID31056398 details
CLPPSLIRPBioGRID31056398 details
CLPPMYG1BioGRID31056398 details
CLPPDCAKDBioGRID31056398 details
CLPPNFU1BioGRID31056398 details
CLPPHSDL2BioGRID31056398 details
CLPPMRPS6BioGRID31056398 details
CLPPNUBPLBioGRID31056398 details
CLPPPAM16BioGRID31056398 details
CLPPGPT2BioGRID31056398 details
CLPPMRPL40BioGRID31056398 details
CLPPLYRM7BioGRID31056398 details
CLPPTACO1BioGRID31056398 details
CLPPTHEM4BioGRID31056398 details
CLPPMRPL44BioGRID31056398 details
CLPPATPAF2BioGRID31056398 details
CLPPMRPS23BioGRID31056398 details
CLPPSFXN4BioGRID31056398 details
CLPPTHNSL1BioGRID31056398 details
CLPPMRPS36BioGRID31056398 details
CLPPMTRF1LBioGRID31056398 details
CLPPNADK2BioGRID31056398 details
CLPPGRPEL1BioGRID31056398 details
CLPPMGME1BioGRID31056398 details
CLPPPDPRBioGRID31056398 details
CLPPIBA57BioGRID31056398 details
CLPPHINT2BioGRID31056398 details
CLPPMRPL54BioGRID31056398 details
CLPPMTPAPBioGRID31056398 details
CLPPMRPL21BioGRID31056398 details
CLPPGTPBP3BioGRID31056398 details
CLPPMRPL10BioGRID31056398 details
CLPPABHD10BioGRID31056398 details
CLPPNUDT19BioGRID31056398 details
CLPPGTPBP10BioGRID31056398 details
CLPPMICU2BioGRID31056398 details
CLPPIARS2BioGRID31056398 details
CLPPHSCBBioGRID33957083 details
CLPPMARS2BioGRID31056398 details
CLPPSPRYD4BioGRID31056398 details
CLPPCOQ8ABioGRID31056398 details
CLPPTRAP1BioGRID34079125 details
CLPPPTPMT1BioGRID31056398 details
CLPPNDUFS7BioGRID31056398 details
CLPPVARS2BioGRID31056398 details
CLPPCOX8ABioGRID34079125 details
CLPPEARS2BioGRID31056398 details
CLPPAARS2BioGRID31056398 34079125 details
CLPPPDE12BioGRID31056398 details
CLPPGATCBioGRID31056398 details
CLPPXPNPEP3BioGRID31056398 details
CLPPMMABBioGRID31056398 details
CLPPMRPS15BioGRID31056398 details
CLPPC8orf82BioGRID31056398 details
CLPPMRPS11BioGRID31056398 details
CLPPTRMT10CBioGRID31056398 details
CLPPNDUFAF5BioGRID31056398 details
CLPPTARS2BioGRID31056398 details
CLPPACAD10BioGRID31056398 details
CLPPRTN4IP1BioGRID31056398 details
CLPPPNPT1BioGRID31056398 details
CLPPNDUFAF2BioGRID31056398 details
CLPPMRPL55BioGRID31056398 details
CLPPFMC1BioGRID31056398 details
CLPPALDH1L2BioGRID31056398 details
CLPPCLYBLBioGRID31056398 details
CLPPZADH2BioGRID31056398 details
CLPPNMNAT3BioGRID31056398 details
CLPPDNAJA3BioGRID33957083 details
CLPPPDHA1BioGRID34079125 details