Entity Details

Primary name CATF_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UBX1
EntryNameCATF_HUMAN
FullNameCathepsin F
TaxID9606
Evidenceevidence at protein level
Length484
SequenceStatuscomplete
DateCreated2001-01-24
DateModified2021-06-02

Ontological Relatives

GenesCTSF

GO terms

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GOName
GO:0004197 cysteine-type endopeptidase activity
GO:0005615 extracellular space
GO:0005764 lysosome
GO:0006508 proteolysis
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0043202 lysosomal lumen
GO:0051603 proteolysis involved in cellular protein catabolic process
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:1903561 extracellular vesicle

Subcellular Location

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Subcellular Location
Lysosome

Domains

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DomainNameCategoryType
IPR000169 Cysteine peptidase, cysteine active siteSiteActive site
IPR000668 Peptidase C1A, papain C-terminalDomainDomain
IPR013201 Cathepsin propeptide inhibitor domain (I29)DomainDomain
IPR025660 Cysteine peptidase, histidine active siteSiteActive site
IPR038765 Papain-like cysteine peptidase superfamilyFamilyHomologous superfamily
IPR039417 Papain-like cysteine endopeptidaseDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB01810 [1-(1-Methyl-4,5-Dioxo-Pent-2-Enylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl EsterDrugbanksmall molecule
DB01871 [1-(1-Benzyl-3-Hydroxy-2-Oxo-Propylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl EsterDrugbanksmall molecule
DB02243 4-Morpholin-4-Yl-Piperidine-1-Carboxylic Acid [1-(3-Benzenesulfonyl-1-Propyl-Allylcarbamoyl)-2-Phenylethyl]-AmideDrugbanksmall molecule
DB03536 Benzyl N-[(2S)-5-(diaminomethylamino)-1-[[(2S)-4-fluoro-3-oxobutan-2-yl]amino]-1-oxopentan-2-yl]carbamateDrugbanksmall molecule
DB03573 WRR-99Drugbanksmall molecule
DB03691 WRR-112Drugbanksmall molecule
DB07913 HOMOPHENYLALANINYLMETHANEDrugbanksmall molecule
DB08775 Benzoyl-tyrosine-alanine-fluoro-methyl ketoneDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CATF_HUMANTRI55_HUMANBioGRID31391242 details
CATF_HUMANHG2A_HUMANHPRD10748235 details