Entity Details

Primary name SRPX2
Entity type gene
Source Source Link

Details

PrimaryID27286
RefseqGeneNG_021337
SymbolSRPX2
Namesushi repeat containing protein X-linked 2
ChromosomeX
LocationXq22.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-01-25
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSRPX2_HUMAN

GO terms

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GOName
GO:0001525 angiogenesis
GO:0005102 signaling receptor binding
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0009986 cell surface
GO:0036458 hepatocyte growth factor binding
GO:0042325 regulation of phosphorylation
GO:0042802 identical protein binding
GO:0048870 cell motility
GO:0051965 positive regulation of synapse assembly
GO:0060076 excitatory synapse
GO:0062023 collagen-containing extracellular matrix
GO:0071625 vocalization behavior
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis
GO:0097060 synaptic membrane
GO:0098609 cell-cell adhesion

Diseases

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Disease IDSourceNameDescription
300643 OMIMRolandic epilepsy with speech dyspraxia and mental retardation X-linked (RESDX)A condition characterized by the association of rolandic seizures with oral and speech dyspraxia, and mental retardation. Rolandic seizures occur during a period of significant brain maturation. During this time, dysfunction of neural network activities such as focal discharges may be associated with specific developmental disabilities resulting in specific cognitive impairments of language, visuo-spatial abilities or attention. The disease may be caused by variants affecting the gene represented in this entry.

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
SRPX2HGFIntAct22242148 details
SRPX2PLAURHPRD18718938 details
SRPX2CTSBHPRD18718938 details
SRPX2ADAMTS4HPRD18718938 details