Entity Details

Primary name PAR14_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ460N5
EntryNamePAR14_HUMAN
FullNameProtein mono-ADP-ribosyltransferase PARP14
TaxID9606
Evidenceevidence at protein level
Length1801
SequenceStatuscomplete
DateCreated2006-07-25
DateModified2021-06-02

Ontological Relatives

GenesPARP14

GO terms

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GOName
GO:0003714 transcription corepressor activity
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006471 protein ADP-ribosylation
GO:0010629 negative regulation of gene expression
GO:0016020 membrane
GO:0019899 enzyme binding
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein
GO:0045087 innate immune response
GO:0060336 negative regulation of interferon-gamma-mediated signaling pathway
GO:0070212 protein poly-ADP-ribosylation
GO:0070403 NAD+ binding
GO:0140289 protein mono-ADP-ribosylation
GO:1902216 positive regulation of interleukin-4-mediated signaling pathway
GO:1990404 protein ADP-ribosylase activity

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR002589 Macro domainDomainDomain
IPR004170 WWE domainDomainDomain
IPR012317 Poly(ADP-ribose) polymerase, catalytic domainDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR034517 PARP-14, RNA recognition motif 2DomainDomain
IPR037197 WWE domain superfamilyFamilyHomologous superfamily
IPR043472 Macro domain-likeFamilyHomologous superfamily

Diseases

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