Entity Details

Primary name SL9A4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6AI14
EntryNameSL9A4_HUMAN
FullNameSodium/hydrogen exchanger 4
TaxID9606
Evidenceevidence at transcript level
Length798
SequenceStatuscomplete
DateCreated2008-01-15
DateModified2021-06-02

Ontological Relatives

GenesSLC9A4

GO terms

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GOName
GO:0001696 gastric acid secretion
GO:0002064 epithelial cell development
GO:0005774 vacuolar membrane
GO:0005886 plasma membrane
GO:0006811 ion transport
GO:0009651 response to salt stress
GO:0015385 sodium:proton antiporter activity
GO:0015386 potassium:proton antiporter activity
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0051453 regulation of intracellular pH
GO:0055075 potassium ion homeostasis
GO:0071805 potassium ion transmembrane transport
GO:0098719 sodium ion import across plasma membrane

Subcellular Location

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Subcellular Location
Apical cell membrane
Basolateral cell membrane
Zymogen granule membrane

Domains

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DomainNameCategoryType
IPR001953 Na+/H+ exchanger, isoform 2 (NHE2)FamilyFamily
IPR004709 Na+/H+ exchangerFamilyFamily
IPR006153 Cation/H+ exchangerDomainDomain
IPR018422 Cation/H+ exchanger, CPA1 familyFamilyFamily
IPR032103 Sodium/hydrogen exchanger, regulatory regionDomainDomain
IPR036958 Na+/H+ exchanger 4FamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
SL9A4_HUMANCHP2_HUMANBioGRID12576672 details
SL9A4_HUMANCHP1_HUMANBioGRID, HPRD12576672 details