Entity Details

Primary name UBP50_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ70EL3
EntryNameUBP50_HUMAN
FullNameInactive ubiquitin carboxyl-terminal hydrolase 50
TaxID9606
Evidenceevidence at transcript level
Length339
SequenceStatuscomplete
DateCreated2006-09-19
DateModified2021-06-02

Ontological Relatives

GenesUSP50

GO terms

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GOName
GO:0004843 thiol-dependent deubiquitinase
GO:0005829 cytosol
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007032 endosome organization
GO:0007265 Ras protein signal transduction
GO:0014069 postsynaptic density
GO:0016579 protein deubiquitination
GO:0019783 ubiquitin-like protein-specific protease activity
GO:0019897 extrinsic component of plasma membrane
GO:0030496 midbody
GO:0031313 extrinsic component of endosome membrane
GO:0032731 positive regulation of interleukin-1 beta production
GO:0035063 nuclear speck organization
GO:0043197 dendritic spine
GO:0070536 protein K63-linked deubiquitination
GO:0071108 protein K48-linked deubiquitination
GO:1900227 positive regulation of NLRP3 inflammasome complex assembly
GO:2001056 positive regulation of cysteine-type endopeptidase activity

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolaseDomainDomain
IPR018200 Ubiquitin specific protease, conserved siteSiteConserved site
IPR028889 Ubiquitin specific protease domainDomainDomain
IPR038765 Papain-like cysteine peptidase superfamilyFamilyHomologous superfamily

Diseases

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