Entity Details

Primary name TAOK1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ7L7X3
EntryNameTAOK1_HUMAN
FullNameSerine/threonine-protein kinase TAO1
TaxID9606
Evidenceevidence at protein level
Length1001
SequenceStatuscomplete
DateCreated2005-10-25
DateModified2021-06-02

Ontological Relatives

GenesTAOK1

GO terms

Show/Hide Table
GOName
GO:0000165 MAPK cascade
GO:0000187 obsolete activation of MAPK activity
GO:0000226 microtubule cytoskeleton organization
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006281 DNA repair
GO:0006468 protein phosphorylation
GO:0006974 cellular response to DNA damage stimulus
GO:0007026 negative regulation of microtubule depolymerization
GO:0007052 mitotic spindle organization
GO:0007095 mitotic G2 DNA damage checkpoint signaling
GO:0007257 obsolete activation of JUN kinase activity
GO:0015630 microtubule cytoskeleton
GO:0016301 kinase activity
GO:0016310 phosphorylation
GO:0016740 transferase activity
GO:0031098 stress-activated protein kinase signaling cascade
GO:0032147 activation of protein kinase activity
GO:0032874 positive regulation of stress-activated MAPK cascade
GO:0032956 regulation of actin cytoskeleton organization
GO:0043014 alpha-tubulin binding
GO:0043539 protein serine/threonine kinase activator activity
GO:0046330 positive regulation of JNK cascade
GO:0046777 protein autophosphorylation
GO:0048156 tau protein binding
GO:0048471 perinuclear region of cytoplasm
GO:0048487 beta-tubulin binding
GO:0048812 neuron projection morphogenesis
GO:0050321 tau-protein kinase activity
GO:0051493 regulation of cytoskeleton organization
GO:0070050 neuron cellular homeostasis
GO:0070062 extracellular exosome
GO:0070507 regulation of microtubule cytoskeleton organization
GO:0097194 execution phase of apoptosis
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1901985 positive regulation of protein acetylation

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB12010 FostamatinibDrugbanksmall molecule