Entity Details

Primary name SETD3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86TU7
EntryNameSETD3_HUMAN
FullNameActin-histidine N-methyltransferase
TaxID9606
Evidenceevidence at protein level
Length594
SequenceStatuscomplete
DateCreated2006-10-31
DateModified2021-06-02

Ontological Relatives

GenesSETD3

GO terms

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GOName
GO:0000785 chromatin
GO:0003713 transcription coactivator activity
GO:0003779 actin binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0010452 histone H3-K36 methylation
GO:0018021 peptidyl-histidine methylation
GO:0018023 peptidyl-lysine trimethylation
GO:0018026 peptidyl-lysine monomethylation
GO:0018027 peptidyl-lysine dimethylation
GO:0018064 protein-L-histidine N-tele-methyltransferase activity
GO:0030047 actin modification
GO:0042800 histone methyltransferase activity (H3-K4 specific)
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046975 histone methyltransferase activity (H3-K36 specific)
GO:0051149 positive regulation of muscle cell differentiation
GO:0070472 regulation of uterine smooth muscle contraction

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001214 SET domainDomainDomain
IPR015353 Rubisco LSMT, substrate-binding domainDomainDomain
IPR025785 Actin-histidine N-methyltransferase SETD3FamilyFamily
IPR036464 Rubisco LSMT, substrate-binding domain superfamilyFamilyHomologous superfamily
IPR044428 SETD3, SET domainDomainDomain

Diseases

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Interactions

5 interactions