Entity Details

Primary name KIBRA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IX03
EntryNameKIBRA_HUMAN
FullNameProtein KIBRA
TaxID9606
Evidenceevidence at protein level
Length1113
SequenceStatuscomplete
DateCreated2006-06-27
DateModified2021-06-02

Ontological Relatives

GenesWWC1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0007221 positive regulation of transcription of Notch receptor target
GO:0016477 cell migration
GO:0019900 kinase binding
GO:0030010 establishment of cell polarity
GO:0032386 regulation of intracellular transport
GO:0032587 ruffle membrane
GO:0032991 protein-containing complex
GO:0035329 hippo signaling
GO:0035330 regulation of hippo signaling
GO:0035331 negative regulation of hippo signaling
GO:0043410 positive regulation of MAPK cascade
GO:0046621 negative regulation of organ growth
GO:0048471 perinuclear region of cytoplasm
GO:0060090 molecular adaptor activity

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001202 WW domainDomainDomain
IPR035892 C2 domain superfamilyFamilyHomologous superfamily
IPR036020 WW domain superfamilyFamilyHomologous superfamily
IPR037771 WWC, C2 domainDomainDomain

Diseases

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Interactions

27 interactions

InteractorPartnerSourcesPublicationsLink
KIBRA_HUMANCDC73_HUMANBioGRID, HPRD, IntAct16169070 details
KIBRA_HUMANF219A_HUMANHPRD, IntAct16169070 details
KIBRA_HUMANAIFM1_HUMANHPRD, IntAct16169070 details
KIBRA_HUMANTNIK_HUMANBioGRID, IntAct17043677 31413325 details
KIBRA_HUMANMK06_HUMANBioGRID, MINT21900206 details
KIBRA_HUMANKPCZ_HUMANBioGRID, HPRD, IntAct15081397 28514442 31980649 details
KIBRA_HUMANEXOC1_HUMANDIP19885391 details
KIBRA_HUMANCDC5L_HUMANBioGRID, IntAct17043677 31413325 details
KIBRA_HUMANLRIF1_HUMANBioGRID, HPRD16169070 details
KIBRA_HUMANRHG07_HUMANBioGRID16684779 24682284 details
KIBRA_HUMANH31_HUMANBioGRID16684779 details
KIBRA_HUMANFEZ1_HUMANBioGRID, HPRD16484223 details
KIBRA_HUMANFEZ2_HUMANBioGRID16484223 details
KIBRA_HUMANWWC2_HUMANBioGRID24682284 details
KIBRA_HUMANWWC3_HUMANBioGRID24682284 details
KIBRA_HUMANDEND_HUMANHPRD12559952 details
KIBRA_HUMANK0513_HUMANHPRD17010949 details
KIBRA_HUMANRIF1_HUMANIntAct16169070 details
KIBRA_HUMAN1433Z_HUMANMINT15161933 details
KIBRA_HUMANPTN14_HUMANBioGRID, IntAct22948661 24366813 25023289 27432908 28514442 28675297 28720576 details
KIBRA_HUMANPTN21_HUMANBioGRID, IntAct27432908 28514442 details
KIBRA_HUMANLATS1_HUMANBioGRID21233212 24682284 25023289 34079125 details
KIBRA_HUMANLATS2_HUMANBioGRID21233212 24682284 details
KIBRA_HUMANMERL_HUMANBioGRID21233212 details
KIBRA_HUMANKPCA_HUMANBioGRID24682284 details
KIBRA_HUMANUSP9X_HUMANBioGRID28720576 details
KIBRA_HUMANKIBRA_HUMANBioGRID18672031 details