Entity Details

Primary name PTGR2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8N8N7
EntryNamePTGR2_HUMAN
FullNameProstaglandin reductase 2
TaxID9606
Evidenceevidence at protein level
Length351
SequenceStatuscomplete
DateCreated2005-04-26
DateModified2021-06-02

Ontological Relatives

GenesPTGR2

GO terms

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GOName
GO:0005737 cytoplasm
GO:0006693 prostaglandin metabolic process
GO:0036132 13-prostaglandin reductase activity
GO:0047522 15-oxoprostaglandin 13-oxidase activity

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR011032 GroES-like superfamilyFamilyHomologous superfamily
IPR013149 Alcohol dehydrogenase, C-terminalDomainDomain
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily
IPR037399 Prostaglandin reductase 2FamilyFamily
IPR041694 Oxidoreductase, N-terminal domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00328 IndomethacinDrugbanksmall molecule
DB07177 (5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACIDDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PTGR2_HUMANBEND5_HUMANBioGRID, IntAct32296183 details