Entity Details

Primary name NNRE_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NCW5
EntryNameNNRE_HUMAN
FullNameNAD(P)H-hydrate epimerase
TaxID9606
Evidenceevidence at protein level
Length288
SequenceStatuscomplete
DateCreated2007-06-26
DateModified2021-06-02

Ontological Relatives

GenesNAXE

GO terms

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GOName
GO:0000166 nucleotide binding
GO:0002040 sprouting angiogenesis
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0006869 lipid transport
GO:0010874 regulation of cholesterol efflux
GO:0016525 negative regulation of angiogenesis
GO:0031580 membrane raft distribution
GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway
GO:0046496 nicotinamide nucleotide metabolic process
GO:0046872 metal ion binding
GO:0052856 NADHX epimerase activity
GO:0052857 NADPHX epimerase activity
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Mitochondrion
Secreted

Domains

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DomainNameCategoryType
IPR004443 YjeF N-terminal domainDomainDomain
IPR032976 YjeF N-terminal domain-containing protein NAXE-likeFamilyFamily
IPR036652 YjeF N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
NNRE_HUMANMK06_HUMANBioGRID, MINT21900206 details
NNRE_HUMANAPOA1_HUMANBioGRID, HPRD11991719 details
NNRE_HUMANAPOA2_HUMANHPRD11991719 details