Entity Details

Primary name WDR48_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TAF3
EntryNameWDR48_HUMAN
FullNameWD repeat-containing protein 48
TaxID9606
Evidenceevidence at protein level
Length677
SequenceStatuscomplete
DateCreated2005-12-20
DateModified2021-06-02

Ontological Relatives

GenesWDR48

GO terms

Show/Hide Table
GOName
GO:0000724 double-strand break repair via homologous recombination
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003697 single-stranded DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005764 lysosome
GO:0005770 late endosome
GO:0005829 cytosol
GO:0006974 cellular response to DNA damage stimulus
GO:0007283 spermatogenesis
GO:0007338 single fertilization
GO:0016032 viral process
GO:0016579 protein deubiquitination
GO:0035264 multicellular organism growth
GO:0036297 interstrand cross-link repair
GO:0042769 DNA damage response, detection of DNA damage
GO:0043130 ubiquitin binding
GO:0043231 intracellular membrane-bounded organelle
GO:0043588 skin development
GO:0048568 embryonic organ development
GO:0048705 skeletal system morphogenesis
GO:0048872 homeostasis of number of cells
GO:0050679 positive regulation of epithelial cell proliferation
GO:0072520 seminiferous tubule development
GO:1902525 regulation of protein monoubiquitination
GO:1903003 positive regulation of protein deubiquitination
GO:1905168 positive regulation of double-strand break repair via homologous recombination

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Late endosome
Lysosome
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR020472 G-protein beta WD-40 repeatRepeatRepeat
IPR021772 WDR48/Bun107FamilyFamily
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

27 interactions

InteractorPartnerSourcesPublicationsLink
WDR48_HUMANUBP12_HUMANBioGRID, IntAct, MINT19075014 19615732 21183687 24145035 24850727 24981860 26462181 26811477 27373336 27463890 27650958 30466959 details
WDR48_HUMANUBP46_HUMANBioGRID, DIP, IntAct, MINT19075014 19615732 21183687 24850727 24981860 25744535 26186194 26388029 27463890 28514442 30466959 details
WDR48_HUMANUBP1_HUMANBioGRID, DIP, IntAct, MINT18082604 19075014 19615732 20147293 22701671 23116119 23463011 24850727 24981860 25744535 26388029 27239033 27463890 27986371 28514442 30335599 30456385 31796584 32951278 details
WDR48_HUMANPHLP1_HUMANBioGRID, IntAct19615732 24145035 25216524 27463890 27880917 details
WDR48_HUMANWDR20_HUMANBioGRID, IntAct, MINT19615732 20147737 24981860 26462181 27463890 28514442 details
WDR48_HUMANR51A1_HUMANBioGRID, IntAct19615732 26186194 27239033 27463890 28514442 29563287 details
WDR48_HUMANPCNA_HUMANBioGRID18082604 details
WDR48_HUMANFANCI_HUMANBioGRID21896657 27239033 details
WDR48_HUMANPAXI1_HUMANBioGRID22990118 details
WDR48_HUMANUBC_HUMANBioGRID26388029 30576655 details
WDR48_HUMANRAD51_HUMANBioGRID27239033 details
WDR48_HUMANNMRL1_HUMANBioGRID31796584 details
WDR48_HUMANHLAB_HUMANIntAct17353931 details
WDR48_HUMANPHLP2_HUMANBioGRID, IntAct19615732 25216524 27463890 27880917 28330616 details
WDR48_HUMANUSH1C_HUMANBioGRID, IntAct27173435 unassigned1312 details
WDR48_HUMANATAD5_HUMANBioGRID20147293 21896657 27239033 details
WDR48_HUMANITCH_HUMANBioGRID22778262 details
WDR48_HUMANFBXL7_HUMANBioGRID24035498 details
WDR48_HUMANANDR_HUMANBioGRID26462181 details
WDR48_HUMANNFAC1_HUMANBioGRID27637333 details
WDR48_HUMANNFAC2_HUMANBioGRID27637333 details
WDR48_HUMANTBK1_HUMANBioGRID29138248 details
WDR48_HUMANRIPK1_HUMANBioGRID29138248 details
WDR48_HUMANULK1_HUMANBioGRID30335599 details
WDR48_HUMANNFAT5_HUMANBioGRID31376680 details
WDR48_HUMANID1_HUMANBioGRID32594826 details
WDR48_HUMANTULP3_HUMANBioGRID33187986 details