Entity Details

Primary name SPIR2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8WWL2
EntryNameSPIR2_HUMAN
FullNameProtein spire homolog 2
TaxID9606
Evidenceevidence at protein level
Length714
SequenceStatuscomplete
DateCreated2008-02-26
DateModified2021-06-02

Ontological Relatives

GenesSPIRE2

GO terms

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GOName
GO:0003779 actin binding
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005938 cell cortex
GO:0015031 protein transport
GO:0016192 vesicle-mediated transport
GO:0030036 actin cytoskeleton organization
GO:0030041 actin filament polymerization
GO:0030659 cytoplasmic vesicle membrane
GO:0032154 cleavage furrow
GO:0036089 cleavage furrow formation
GO:0040038 polar body extrusion after meiotic divisions
GO:0045010 actin nucleation
GO:0046907 intracellular transport
GO:0048193 Golgi vesicle transport
GO:0051295 establishment of meiotic spindle localization
GO:0051639 actin filament network formation
GO:0070649 formin-nucleated actin cable assembly
GO:2000781 positive regulation of double-strand break repair

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Cytoplasmic vesicle membrane

Domains

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DomainNameCategoryType
IPR003124 WH2 domainDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR011019 KIND domainDomainDomain
IPR029901 Protein SpireFamilyFamily
IPR029904 Protein Spire2FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB08080 Latrunculin BDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SPIR2_HUMANHGS_HUMANBioGRID, IntAct32296183 details