Entity Details

Primary name NCAN_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14594
EntryNameNCAN_HUMAN
FullNameNeurocan core protein
TaxID9606
Evidenceevidence at protein level
Length1321
SequenceStatuscomplete
DateCreated2003-01-27
DateModified2021-06-02

Ontological Relatives

GenesNCAN

GO terms

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GOName
GO:0001501 skeletal system development
GO:0005509 calcium ion binding
GO:0005540 hyaluronic acid binding
GO:0005576 extracellular region
GO:0005796 Golgi lumen
GO:0007155 cell adhesion
GO:0007417 central nervous system development
GO:0030198 extracellular matrix organization
GO:0030206 chondroitin sulfate biosynthetic process
GO:0030207 chondroitin sulfate catabolic process
GO:0030208 dermatan sulfate biosynthetic process
GO:0030246 carbohydrate binding
GO:0031012 extracellular matrix
GO:0043202 lysosomal lumen

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000436 Sushi/SCR/CCP domainDomainDomain
IPR000538 Link domainDomainDomain
IPR000742 EGF-like domainDomainDomain
IPR001304 C-type lectin-likeDomainDomain
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR016186 C-type lectin-like/link domain superfamilyFamilyHomologous superfamily
IPR016187 C-type lectin foldFamilyHomologous superfamily
IPR018097 EGF-like calcium-binding, conserved siteSiteConserved site
IPR018378 C-type lectin, conserved siteSiteConserved site
IPR035976 Sushi/SCR/CCP superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB02379 Beta-D-GlucoseDrugbanksmall molecule
DB04396 ThiodigalactosideDrugbanksmall molecule
DB08818 Hyaluronic acidDrugbanksmall molecule