Entity Details

Primary name NR4A3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92570
EntryNameNR4A3_HUMAN
FullNameNuclear receptor subfamily 4 group A member 3
TaxID9606
Evidenceevidence at protein level
Length626
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesNR4A3

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003707 steroid hormone receptor activity
GO:0004879 nuclear receptor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0007369 gastrulation
GO:0008270 zinc ion binding
GO:0009444 pyruvate oxidation
GO:0010613 positive regulation of cardiac muscle hypertrophy
GO:0010828 positive regulation of glucose transmembrane transport
GO:0019901 protein kinase binding
GO:0031100 animal organ regeneration
GO:0032765 positive regulation of mast cell cytokine production
GO:0035259 glucocorticoid receptor binding
GO:0035497 cAMP response element binding
GO:0035726 common myeloid progenitor cell proliferation
GO:0038097 positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway
GO:0042803 protein homodimerization activity
GO:0043303 mast cell degranulation
GO:0044320 cellular response to leptin stimulus
GO:0045333 cellular respiration
GO:0045444 fat cell differentiation
GO:0045652 regulation of megakaryocyte differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046321 positive regulation of fatty acid oxidation
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0048660 regulation of smooth muscle cell proliferation
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0050679 positive regulation of epithelial cell proliferation
GO:0061469 regulation of type B pancreatic cell proliferation
GO:0071376 cellular response to corticotropin-releasing hormone stimulus
GO:0071870 cellular response to catecholamine stimulus
GO:0097009 energy homeostasis
GO:1900625 positive regulation of monocyte aggregation
GO:1903208 negative regulation of hydrogen peroxide-induced neuron death
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation
GO:1904754 positive regulation of vascular associated smooth muscle cell migration
GO:2000253 positive regulation of feeding behavior

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000536 Nuclear hormone receptor, ligand-binding domainDomainDomain
IPR001628 Zinc finger, nuclear hormone receptor-typeDomainDomain
IPR001723 Nuclear hormone receptorFamilyFamily
IPR003070 Orphan nuclear receptorFamilyFamily
IPR003072 Orphan nuclear receptor, NOR1 typeFamilyFamily
IPR013088 Zinc finger, NHR/GATA-typeFamilyHomologous superfamily
IPR035500 Nuclear hormone receptor-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01254 DasatinibDrugbanksmall molecule

Interactions

44 interactions

InteractorPartnerSourcesPublicationsLink
NR4A3_HUMANKRA56_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANPCSK5_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANKPRP_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANLCE2B_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANKRA92_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANKR105_HUMANIntAct32296183 details
NR4A3_HUMANUBE3A_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANLCE2D_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANCDN2D_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANSMOC1_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANNECT2_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANKR411_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANCRTP1_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANMACOI_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANKRA44_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANVASN_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANPPB1_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANTSN4_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANKR124_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANPIN1_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANCHRD_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANKRA59_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANKRA98_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANKR511_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANZN330_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANVWC2L_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMAN3BHS7_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANKR123_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANATL4_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANKRA42_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANFBLN3_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANKRA53_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANKRA93_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANKR108_HUMANBioGRID, IntAct32296183 details
NR4A3_HUMANSIX3_HUMANBioGRID, HPRD, UniProt11173923 12543801 15523651 details
NR4A3_HUMANTIF1B_HUMANBioGRID19321449 details
NR4A3_HUMANCSN5_HUMANBioGRID, HPRD15604093 details
NR4A3_HUMANRECK_HUMANBioGRID32296183 details
NR4A3_HUMANKR101_HUMANBioGRID32296183 details
NR4A3_HUMANCP21A_HUMANBioGRID32296183 details
NR4A3_HUMANBCL2_HUMANMINT30455429 details
NR4A3_HUMANKDM5B_HUMANBioGRID19336002 details
NR4A3_HUMANKS6A1_HUMANHPRD16223362 details
NR4A3_HUMANVHL_HUMANHPRD18305400 details