Entity Details

Primary name EXT2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ93063
EntryNameEXT2_HUMAN
FullNameExostosin-2
TaxID9606
Evidenceevidence at protein level
Length718
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesEXT2

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0001503 ossification
GO:0001707 mesoderm formation
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005794 Golgi apparatus
GO:0006024 glycosaminoglycan biosynthetic process
GO:0006487 protein N-linked glycosylation
GO:0007165 signal transduction
GO:0008217 regulation of blood pressure
GO:0010467 gene expression
GO:0015012 heparan sulfate proteoglycan biosynthetic process
GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process
GO:0015020 glucuronosyltransferase activity
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016757 glycosyltransferase activity
GO:0030154 cell differentiation
GO:0030210 heparin biosynthetic process
GO:0033692 cellular polysaccharide biosynthetic process
GO:0042044 fluid transport
GO:0042311 vasodilation
GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity
GO:0043541 UDP-N-acetylglucosamine transferase complex
GO:0044344 cellular response to fibroblast growth factor stimulus
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity
GO:0050891 multicellular organismal water homeostasis
GO:0051923 sulfation
GO:0055078 sodium ion homeostasis
GO:0060047 heart contraction
GO:0060350 endochondral bone morphogenesis
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Golgi apparatus membrane

Domains

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DomainNameCategoryType
IPR004263 Exostosin-likeFamilyFamily
IPR015338 Glycosyl transferase 64 domainDomainDomain
IPR027673 Exostosin-2FamilyFamily
IPR029044 Nucleotide-diphospho-sugar transferasesFamilyHomologous superfamily
IPR040911 Exostosin, GT47 domainDomainDomain

Diseases

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