Entity Details

Primary name FFAR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO14842
EntryNameFFAR1_HUMAN
FullNameFree fatty acid receptor 1
TaxID9606
Evidenceevidence at protein level
Length300
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesFFAR1

GO terms

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GOName
GO:0004930 G protein-coupled receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0008289 lipid binding
GO:0030073 insulin secretion
GO:0032024 positive regulation of insulin secretion
GO:0032691 negative regulation of interleukin-1 beta production
GO:0042593 glucose homeostasis
GO:0045125 bioactive lipid receptor activity
GO:0050796 regulation of insulin secretion
GO:0051928 positive regulation of calcium ion transport
GO:0070542 response to fatty acid

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR013312 G protein-coupled receptor 40-related receptorFamilyFamily
IPR013313 GPR40 receptor fatty acidFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00159 IcosapentDrugbanksmall molecule

Interactions

2 interactions