Entity Details

Primary name DGAT2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96PD7
EntryNameDGAT2_HUMAN
FullNameDiacylglycerol O-acyltransferase 2
TaxID9606
Evidenceevidence at protein level
Length388
SequenceStatuscomplete
DateCreated2006-09-05
DateModified2021-06-02

Ontological Relatives

GenesDGAT2

GO terms

Show/Hide Table
GOName
GO:0003846 2-acylglycerol O-acyltransferase activity
GO:0004144 diacylglycerol O-acyltransferase activity
GO:0005739 mitochondrion
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005811 lipid droplet
GO:0005829 cytosol
GO:0006071 glycerol metabolic process
GO:0006629 lipid metabolic process
GO:0006640 monoacylglycerol biosynthetic process
GO:0006651 diacylglycerol biosynthetic process
GO:0008374 O-acyltransferase activity
GO:0010867 positive regulation of triglyceride biosynthetic process
GO:0016021 integral component of membrane
GO:0019432 triglyceride biosynthetic process
GO:0019915 lipid storage
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0034383 low-density lipoprotein particle clearance
GO:0035336 long-chain fatty-acyl-CoA metabolic process
GO:0035356 cellular triglyceride homeostasis
GO:0036155 acylglycerol acyl-chain remodeling
GO:0038183 bile acid signaling pathway
GO:0042632 cholesterol homeostasis
GO:0042803 protein homodimerization activity
GO:0043231 intracellular membrane-bounded organelle
GO:0045722 positive regulation of gluconeogenesis
GO:0046322 negative regulation of fatty acid oxidation
GO:0046339 diacylglycerol metabolic process
GO:0048471 perinuclear region of cytoplasm
GO:0050252 retinol O-fatty-acyltransferase activity
GO:0050746 regulation of lipoprotein metabolic process
GO:0055089 fatty acid homeostasis
GO:0060613 fat pad development
GO:0071400 cellular response to oleic acid
GO:0090181 regulation of cholesterol metabolic process
GO:0097006 regulation of plasma lipoprotein particle levels
GO:1990578 perinuclear endoplasmic reticulum membrane

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Endoplasmic reticulum membrane
Lipid droplet

Domains

Show/Hide Table
DomainNameCategoryType
IPR007130 Diacylglycerol acyltransferaseFamilyFamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB08949 Inositol nicotinateDrugbanksmall molecule
DB09568 Omega-3-carboxylic acidsDrugbanksmall molecule
DB13961 Fish oilDrugbankbiotech

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
DGAT2_HUMANTERA_HUMANBioGRID, MINT24820123 details
DGAT2_HUMANAMFR_HUMANBioGRID, MINT24820123 details