Entity Details

Primary name FSP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BRQ8
EntryNameFSP1_HUMAN
FullNameFerroptosis suppressor protein 1
TaxID9606
Evidenceevidence at protein level
Length373
SequenceStatuscomplete
DateCreated2006-05-30
DateModified2021-06-02

Ontological Relatives

GenesAIFM2

GO terms

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GOName
GO:0003677 DNA binding
GO:0004174 electron-transferring-flavoprotein dehydrogenase activity
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005811 lipid droplet
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006743 ubiquinone metabolic process
GO:0008637 apoptotic mitochondrial changes
GO:0016021 integral component of membrane
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0042981 regulation of apoptotic process
GO:0043065 positive regulation of apoptotic process
GO:0050660 flavin adenine dinucleotide binding
GO:0110076 negative regulation of ferroptosis
GO:1900407 regulation of cellular response to oxidative stress

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Lipid droplet
Mitochondrion membrane
Nucleus

Domains

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DomainNameCategoryType
IPR023753 FAD/NAD(P)-binding domainDomainDomain
IPR036188 FAD/NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
FSP1_HUMANTRI69_HUMANBioGRID, IntAct32296183 details
FSP1_HUMANCNPY4_HUMANBioGRID, IntAct32296183 details
FSP1_HUMANTRI54_HUMANBioGRID, IntAct32296183 details