Entity Details

Primary name LGR4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BXB1
EntryNameLGR4_HUMAN
FullNameLeucine-rich repeat-containing G-protein coupled receptor 4
TaxID9606
Evidenceevidence at protein level
Length951
SequenceStatuscomplete
DateCreated2002-06-20
DateModified2021-06-02

Ontological Relatives

GenesLGR4

GO terms

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GOName
GO:0001649 osteoblast differentiation
GO:0001818 negative regulation of cytokine production
GO:0001942 hair follicle development
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007190 activation of adenylate cyclase activity
GO:0007283 spermatogenesis
GO:0008528 G protein-coupled peptide receptor activity
GO:0009755 hormone-mediated signaling pathway
GO:0016500 protein-hormone receptor activity
GO:0030282 bone mineralization
GO:0030539 male genitalia development
GO:0032922 circadian regulation of gene expression
GO:0034122 negative regulation of toll-like receptor signaling pathway
GO:0036335 intestinal stem cell homeostasis
GO:0045087 innate immune response
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046849 bone remodeling
GO:0048565 digestive tract development
GO:0061290 canonical Wnt signaling pathway involved in metanephric kidney development
GO:0072202 cell differentiation involved in metanephros development
GO:0072224 metanephric glomerulus development
GO:0072282 metanephric nephron tubule morphogenesis
GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0120163 negative regulation of cold-induced thermogenesis
GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000372 Leucine-rich repeat N-terminal domainDomainDomain
IPR001611 Leucine-rich repeatRepeatRepeat
IPR002131 Glycoprotein hormone receptor familyFamilyFamily
IPR003591 Leucine-rich repeat, typical subtypeRepeatRepeat
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily

Diseases

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