Entity Details

Primary name ACH10_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9GZZ6
EntryNameACH10_HUMAN
FullNameNeuronal acetylcholine receptor subunit alpha-10
TaxID9606
Evidenceevidence at protein level
Length450
SequenceStatuscomplete
DateCreated2001-07-11
DateModified2021-06-02

Ontological Relatives

GenesCHRNA10

GO terms

Show/Hide Table
GOName
GO:0004888 transmembrane signaling receptor activity
GO:0005102 signaling receptor binding
GO:0005262 calcium channel activity
GO:0005887 integral component of plasma membrane
GO:0007165 signal transduction
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007268 chemical synaptic transmission
GO:0007271 synaptic transmission, cholinergic
GO:0016020 membrane
GO:0022848 acetylcholine-gated cation-selective channel activity
GO:0030424 axon
GO:0030594 neurotransmitter receptor activity
GO:0034220 ion transmembrane transport
GO:0042127 regulation of cell population proliferation
GO:0042391 regulation of membrane potential
GO:0042472 inner ear morphogenesis
GO:0043005 neuron projection
GO:0043204 perikaryon
GO:0045202 synapse
GO:0050877 nervous system process
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0098981 cholinergic synapse
GO:0099060 integral component of postsynaptic specialization membrane

Subcellular Location

Show/Hide Table
Subcellular Location
Cell junction
Cell membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR002394 Nicotinic acetylcholine receptorFamilyFamily
IPR006029 Neurotransmitter-gated ion-channel transmembrane domainDomainDomain
IPR006201 Neurotransmitter-gated ion-channelFamilyFamily
IPR006202 Neurotransmitter-gated ion-channel ligand-binding domainDomainDomain
IPR018000 Neurotransmitter-gated ion-channel, conserved siteSiteConserved site
IPR036719 Neurotransmitter-gated ion-channel transmembrane domain superfamilyFamilyHomologous superfamily
IPR036734 Neurotransmitter-gated ion-channel ligand-binding domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB00184 NicotineDrugbanksmall molecule
DB00202 SuccinylcholineDrugbanksmall molecule
DB00237 ButabarbitalDrugbanksmall molecule
DB00898 EthanolDrugbanksmall molecule
DB01090 PentoliniumDrugbanksmall molecule
DB01116 TrimethaphanDrugbanksmall molecule
DB05069 ATG003Drugbanksmall molecule
DB05137 LobelineDrugbanksmall molecule
DB05740 RPI-78MDrugbanksmall molecule
DB14783 Diroximel fumarateDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink