Entity Details

Primary name GBP3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H0R5
EntryNameGBP3_HUMAN
FullNameGuanylate-binding protein 3
TaxID9606
Evidenceevidence at protein level
Length595
SequenceStatuscomplete
DateCreated2006-11-28
DateModified2021-06-02

Ontological Relatives

GenesGBP3

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0031410 cytoplasmic vesicle
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0048471 perinuclear region of cytoplasm
GO:0051607 defense response to virus
GO:0071346 cellular response to interferon-gamma
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor

Subcellular Location

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Subcellular Location
Cytoplasm
Golgi apparatus membrane

Domains

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DomainNameCategoryType
IPR003191 Guanylate-binding protein/Atlastin, C-terminalDomainDomain
IPR015894 Guanylate-binding protein, N-terminalDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR030386 GB1/RHD3-type guanine nucleotide-binding (G) domainDomainDomain
IPR036543 Guanylate-binding protein, C-terminal domain superfamilyFamilyHomologous superfamily
IPR037684 Guanylate-binding protein, C-terminalDomainDomain

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
GBP3_HUMANM4K4_HUMANBioGRID, HPRD, MINT12387898 details
GBP3_HUMANGBP2_HUMANBioGRID, IntAct, UniProt21151871 28514442 details
GBP3_HUMANGBP1_HUMANBioGRID, IntAct, UniProt21151871 28514442 details
GBP3_HUMANGBP3_HUMANUniProt21151871 details
GBP3_HUMANGBP5_HUMANUniProt21151871 details