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Entity Details
Primary name
HIPK3_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q9H422
EntryName
HIPK3_HUMAN
FullName
Homeodomain-interacting protein kinase 3
TaxID
9606
Evidence
evidence at protein level
Length
1215
SequenceStatus
complete
DateCreated
2005-03-15
DateModified
2021-06-02
Ontological Relatives
Genes
HIPK3
GO terms
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GO
Name
GO:0004672
protein kinase activity
GO:0004674
protein serine/threonine kinase activity
GO:0004713
protein tyrosine kinase activity
GO:0005524
ATP binding
GO:0005634
nucleus
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0005886
plasma membrane
GO:0006468
protein phosphorylation
GO:0006915
apoptotic process
GO:0009299
mRNA transcription
GO:0016604
nuclear body
GO:0016605
PML body
GO:0018105
peptidyl-serine phosphorylation
GO:0018107
peptidyl-threonine phosphorylation
GO:0043066
negative regulation of apoptotic process
GO:0043508
negative regulation of JUN kinase activity
GO:0106310
protein serine kinase activity
GO:0106311
protein threonine kinase activity
Subcellular Location
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Subcellular Location
Cytoplasm
Nucleus
Domains
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Domain
Name
Category
Type
IPR000719
Protein kinase domain
Domain
Domain
IPR008271
Serine/threonine-protein kinase, active site
Site
Active site
IPR011009
Protein kinase-like domain superfamily
Family
Homologous superfamily
IPR017441
Protein kinase, ATP binding site
Site
Binding site
Diseases
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Drugs
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Drug
Name
Source
Type
DB12010
Fostamatinib
Drugbank
small molecule
Interactions
31 interactions
Interactor
Partner
Sources
Publications
Link
HIPK3_HUMAN
COT2_HUMAN
BioGRID, HPRD, MINT
15231748
details
HIPK3_HUMAN
TOX4_HUMAN
BioGRID, HPRD, MINT
15231748
details
HIPK3_HUMAN
HEYL_HUMAN
BioGRID, HPRD, MINT
15231748
details
HIPK3_HUMAN
MTMR4_HUMAN
BioGRID, HPRD, MINT
15231748
details
HIPK3_HUMAN
TGFI1_HUMAN
BioGRID, HPRD, MINT
15231748
details
HIPK3_HUMAN
ZYX_HUMAN
BioGRID, HPRD, MINT
15231748
details
HIPK3_HUMAN
LIMK2_HUMAN
BioGRID, HPRD, MINT
15231748
details
HIPK3_HUMAN
C1QA_HUMAN
BioGRID, HPRD, MINT
15231748
details
HIPK3_HUMAN
SIAH1_HUMAN
BioGRID, HPRD, MINT
15231748
details
HIPK3_HUMAN
LIMS2_HUMAN
BioGRID, HPRD, MINT
15231748
details
HIPK3_HUMAN
ARRB2_HUMAN
BioGRID, HPRD, MINT
15231748
details
HIPK3_HUMAN
ZN107_HUMAN
BioGRID, HPRD, MINT
15231748
details
HIPK3_HUMAN
LIMD1_HUMAN
BioGRID, HPRD, MINT
15231748
details
HIPK3_HUMAN
SIAH2_HUMAN
BioGRID, HPRD, MINT
15231748
details
HIPK3_HUMAN
GORS1_HUMAN
BioGRID, HPRD, MINT
15231748
details
HIPK3_HUMAN
CREB1_HUMAN
BioGRID, IntAct
20936779
details
HIPK3_HUMAN
GLNA_HUMAN
BioGRID, IntAct
20936779
details
HIPK3_HUMAN
GRB2_HUMAN
BioGRID, IntAct
20936779
details
HIPK3_HUMAN
UBC9_HUMAN
BioGRID, IntAct
20936779
details
HIPK3_HUMAN
P53_HUMAN
BioGRID, IntAct
10961991
23602568
details
HIPK3_HUMAN
P73_HUMAN
BioGRID
10961991
details
HIPK3_HUMAN
SUMO1_HUMAN
BioGRID, HPRD
10961991
details
HIPK3_HUMAN
TNR6_HUMAN
BioGRID, HPRD
11034606
details
HIPK3_HUMAN
CBP_HUMAN
BioGRID
28680062
details
HIPK3_HUMAN
ANDR_HUMAN
HPRD
9725910
details
HIPK3_HUMAN
MBD1_HUMAN
HPRD
15231748
details
HIPK3_HUMAN
SKIL_HUMAN
HPRD
15231748
details
HIPK3_HUMAN
FLNC_HUMAN
HPRD
15231748
details
HIPK3_HUMAN
RGS3_HUMAN
HPRD
15231748
details
HIPK3_HUMAN
SNIP1_HUMAN
HPRD
15231748
details
HIPK3_HUMAN
FADD_HUMAN
BioGRID, HPRD
10640736
11034606
details
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