Entity Details

Primary name TF7L1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9HCS4
EntryNameTF7L1_HUMAN
FullNameTranscription factor 7-like 1
TaxID9606
Evidenceevidence at transcript level
Length588
SequenceStatuscomplete
DateCreated2003-03-25
DateModified2021-06-02

Ontological Relatives

GenesTCF7L1

GO terms

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GOName
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006325 chromatin organization
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008013 beta-catenin binding
GO:0030111 regulation of Wnt signaling pathway
GO:0060070 canonical Wnt signaling pathway
GO:1904837 beta-catenin-TCF complex assembly
GO:1990837 sequence-specific double-stranded DNA binding
GO:1990907 beta-catenin-TCF complex

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR009071 High mobility group box domainDomainDomain
IPR013558 CTNNB1 binding, N-teminalDomainDomain
IPR024940 Transcription factor TCF/LEFFamilyFamily
IPR027397 Catenin binding domain superfamilyFamilyHomologous superfamily
IPR028778 Transcription factor 7-like 1FamilyFamily
IPR036910 High mobility group box domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
TF7L1_HUMANCTNB1_HUMANBioGRID, HPRD, Molecular Connections11136974 11266540 15327769 29540185 details
TF7L1_HUMANDAZP2_HUMANBioGRID19304756 details
TF7L1_HUMANPJA2_HUMANBioGRID30021253 details