Entity Details

Primary name RTN4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NQC3
EntryNameRTN4_HUMAN
FullNameReticulon-4
TaxID9606
Evidenceevidence at protein level
Length1192
SequenceStatuscomplete
DateCreated2001-11-16
DateModified2021-06-02

Ontological Relatives

GenesRTN4

GO terms

Show/Hide Table
GOName
GO:0001825 blastocyst formation
GO:0002523 leukocyte migration involved in inflammatory response
GO:0003723 RNA binding
GO:0005635 nuclear envelope
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0006915 apoptotic process
GO:0007029 endoplasmic reticulum organization
GO:0007413 axonal fasciculation
GO:0010634 positive regulation of epithelial cell migration
GO:0014069 postsynaptic density
GO:0021801 cerebral cortex radial glia-guided migration
GO:0022009 central nervous system vasculogenesis
GO:0030054 cell junction
GO:0030176 integral component of endoplasmic reticulum membrane
GO:0030308 negative regulation of cell growth
GO:0030334 regulation of cell migration
GO:0030517 negative regulation of axon extension
GO:0031625 ubiquitin protein ligase binding
GO:0033601 positive regulation of mammary gland epithelial cell proliferation
GO:0034165 positive regulation of toll-like receptor 9 signaling pathway
GO:0035022 positive regulation of Rac protein signal transduction
GO:0035441 cell migration involved in vasculogenesis
GO:0042803 protein homodimerization activity
GO:0042981 regulation of apoptotic process
GO:0042995 cell projection
GO:0043025 neuronal cell body
GO:0045296 cadherin binding
GO:0045766 positive regulation of angiogenesis
GO:0050771 negative regulation of axonogenesis
GO:0050821 protein stabilization
GO:0051292 nuclear pore complex assembly
GO:0051897 positive regulation of protein kinase B signaling
GO:0060317 cardiac epithelial to mesenchymal transition
GO:0060907 positive regulation of macrophage cytokine production
GO:0061462 protein localization to lysosome
GO:0071456 cellular response to hypoxia
GO:0071782 endoplasmic reticulum tubular network
GO:0071786 endoplasmic reticulum tubular network organization
GO:0071787 endoplasmic reticulum tubular network formation
GO:0090156 cellular sphingolipid homeostasis
GO:0098826 endoplasmic reticulum tubular network membrane
GO:0120078 cell adhesion involved in sprouting angiogenesis
GO:1902430 negative regulation of amyloid-beta formation
GO:1902624 positive regulation of neutrophil migration
GO:1905523 positive regulation of macrophage migration
GO:1905552 positive regulation of protein localization to endoplasmic reticulum
GO:1905580 positive regulation of ERBB3 signaling pathway
GO:1905653 positive regulation of artery morphogenesis
GO:1990809 endoplasmic reticulum tubular network membrane organization
GO:2000172 regulation of branching morphogenesis of a nerve
GO:2000347 positive regulation of hepatocyte proliferation
GO:2001213 negative regulation of vasculogenesis

Subcellular Location

Show/Hide Table
Subcellular Location
Cell junction
Cell membrane
Endoplasmic reticulum membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR003388 ReticulonDomainDomain

Diseases

Show/Hide Table

Interactions

64 interactions

InteractorPartnerSourcesPublicationsLink
RTN4_HUMANAMRP_HUMANBioGRID, HPRD, IntAct16169070 details
RTN4_HUMANDPYL1_HUMANBioGRID, HPRD, IntAct16169070 details
RTN4_HUMANPRR13_HUMANBioGRID, IntAct16169070 details
RTN4_HUMANLRCH4_HUMANBioGRID, HPRD, IntAct16189514 details
RTN4_HUMANPKHF2_HUMANBioGRID, HPRD, IntAct16189514 details
RTN4_HUMANRTN3_HUMANBioGRID, HPRD, IntAct12811824 16189514 25416956 28514442 32296183 details
RTN4_HUMANSNAA_HUMANBioGRID, HPRD, IntAct16189514 details
RTN4_HUMANSPG21_HUMANBioGRID, HPRD, IntAct16189514 31515488 details
RTN4_HUMANFXR2_HUMANBioGRID, HPRD, IntAct16189514 details
RTN4_HUMANRB33A_HUMANBioGRID, HPRD, IntAct16189514 details
RTN4_HUMANCERT_HUMANBioGRID, HPRD, IntAct16189514 29892012 31515488 details
RTN4_HUMANABL1_HUMANIntAct17474147 details
RTN4_HUMANSRC_HUMANIntAct17474147 details
RTN4_HUMANFYN_HUMANIntAct17474147 details
RTN4_HUMANNCK2_HUMANMINT16752908 details
RTN4_HUMANSNX15_HUMANBioGRID, IntAct, MINT21516116 25416956 details
RTN4_HUMANLAMA4_HUMANBioGRID, IntAct21988832 details
RTN4_HUMANBAIP2_HUMANBioGRID, IntAct21988832 details
RTN4_HUMANDPB1_HUMANBioGRID, MINT21900206 details
RTN4_HUMANNR4A1_HUMANBioGRID, MINT21900206 details
RTN4_HUMANRS27_HUMANBioGRID, MINT21900206 details
RTN4_HUMANSNX1_HUMANBioGRID, IntAct25416956 26344197 details
RTN4_HUMANSYT16_HUMANBioGRID, IntAct25416956 29892012 31515488 details
RTN4_HUMANZFY21_HUMANBioGRID, IntAct25416956 details
RTN4_HUMANAR6P1_HUMANBioGRID, IntAct25416956 26186194 28514442 details
RTN4_HUMANRTN4_HUMANBioGRID, IntAct25416956 details
RTN4_HUMANWWTR1_HUMANIntAct25416956 details
RTN4_HUMANTERF1_HUMANbhf-ucl, BioGRID21044950 details
RTN4_HUMANPOTE1_HUMANbhf-ucl, BioGRID21044950 details
RTN4_HUMAN5HT2C_HUMANBioGRID, IntAct, MINT28298427 28514442 details
RTN4_HUMANBKRB1_HUMANBioGRID, MINT28298427 details
RTN4_HUMANCCR4_HUMANBioGRID, MINT28298427 details
RTN4_HUMANCLTR2_HUMANBioGRID, MINT28298427 details
RTN4_HUMANDRD2_HUMANBioGRID, MINT28298427 details
RTN4_HUMANPAR2_HUMANBioGRID, MINT28298427 details
RTN4_HUMANGPR35_HUMANBioGRID, MINT28298427 details
RTN4_HUMANACM4_HUMANBioGRID, MINT28298427 details
RTN4_HUMANMEP1B_HUMANUniProt27180358 details
RTN4_HUMANERBB2_HUMANBioGRID, IntAct31980649 details
RTN4_HUMANERBB3_HUMANBioGRID, IntAct31980649 details
RTN4_HUMANERBB4_HUMANBioGRID, IntAct31980649 details
RTN4_HUMANBCL2_HUMANBioGRID, HPRD11126360 17191123 details
RTN4_HUMANB2CL1_HUMANBioGRID, HPRD11126360 details
RTN4_HUMANRT4I1_HUMANBioGRID, HPRD12067236 details
RTN4_HUMANQCR1_HUMANBioGRID, HPRD12067236 details
RTN4_HUMANQCR2_HUMANBioGRID, HPRD12067236 details
RTN4_HUMANWWP1_HUMANBioGRID19035836 details
RTN4_HUMANCLN8_HUMANBioGRID23142642 details
RTN4_HUMANGLP1R_HUMANBioGRID26272612 details
RTN4_HUMANLMNA_HUMANBioGRID24623722 details
RTN4_HUMANOGT1_HUMANBioGRID32994395 details
RTN4_HUMANNDKB_HUMANIntAct17353931 details
RTN4_HUMANAAKB1_HUMANIntAct17353931 details
RTN4_HUMANTRAF6_HUMANIntAct17353931 details
RTN4_HUMANATLA1_HUMANIntAct19665976 details
RTN4_HUMANNGBR_HUMANDIP16835300 details
RTN4_HUMANBACE1_HUMANBioGRID, UniProt16965550 details
RTN4_HUMANCNTP1_HUMANBioGRID, HPRD14592966 details
RTN4_HUMANKCNA1_HUMANBioGRID14592966 details
RTN4_HUMANKCNA2_HUMANBioGRID14592966 details
RTN4_HUMANRNF41_HUMANBioGRID27353365 details
RTN4_HUMANTBA4A_HUMANHPRD12377379 details
RTN4_HUMANRTN4R_HUMANHPRD11201742 details
RTN4_HUMANMBP_HUMANHPRD12377379 details