Entity Details

Primary name MGA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO43451
EntryNameMGA_HUMAN
FullNameMaltase-glucoamylase, intestinal
TaxID9606
Evidenceevidence at protein level
Length1857
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesMGAM

GO terms

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GOName
GO:0003824 catalytic activity
GO:0004339 glucan 1,4-alpha-glucosidase activity
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004558 alpha-1,4-glucosidase activity
GO:0005886 plasma membrane
GO:0005983 starch catabolic process
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0030246 carbohydrate binding
GO:0032450 maltose alpha-glucosidase activity
GO:0043312 neutrophil degranulation
GO:0044245 polysaccharide digestion
GO:0070062 extracellular exosome
GO:0070821 tertiary granule membrane
GO:0101003 ficolin-1-rich granule membrane

Subcellular Location

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Subcellular Location
Apical cell membrane

Domains

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DomainNameCategoryType
IPR000322 Glycoside hydrolase family 31FamilyFamily
IPR000519 P-type trefoil domainDomainDomain
IPR011013 Galactose mutarotase-like domain superfamilyFamilyHomologous superfamily
IPR013780 Glycosyl hydrolase, all-betaFamilyHomologous superfamily
IPR017853 Glycoside hydrolase superfamilyFamilyHomologous superfamily
IPR017957 P-type trefoil, conserved siteSiteConserved site
IPR030458 Glycosyl hydrolases family 31, active siteSiteActive site
IPR030459 Glycosyl hydrolases family 31, conserved siteSiteConserved site
IPR031727 Galactose mutarotase, N-terminal barrelDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00284 AcarboseDrugbanksmall molecule
DB00491 MiglitolDrugbanksmall molecule
DB04878 VogliboseDrugbanksmall molecule

Interactions

7 interactions