Entity Details

Primary name ADA21_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UKJ8
EntryNameADA21_HUMAN
FullNameDisintegrin and metalloproteinase domain-containing protein 21
TaxID9606
Evidenceevidence at protein level
Length722
SequenceStatuscomplete
DateCreated2001-06-01
DateModified2021-06-02

Ontological Relatives

GenesADAM21

GO terms

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GOName
GO:0004222 metalloendopeptidase activity
GO:0005886 plasma membrane
GO:0007338 single fertilization
GO:0007339 binding of sperm to zona pellucida
GO:0008237 metallopeptidase activity
GO:0008584 male gonad development
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
GO:0046872 metal ion binding
GO:1990913 sperm head plasma membrane

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000742 EGF-like domainDomainDomain
IPR001590 Peptidase M12B, ADAM/reprolysinDomainDomain
IPR001762 Disintegrin domainDomainDomain
IPR002870 Peptidase M12B, propeptideDomainDomain
IPR006586 ADAM, cysteine-rich domainDomainDomain
IPR018358 Disintegrin, conserved siteSiteConserved site
IPR024079 Metallopeptidase, catalytic domain superfamilyFamilyHomologous superfamily
IPR034027 Reprolysin domain, adamalysin-typeDomainDomain
IPR036436 Disintegrin domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ADA21_HUMANCNR2_HUMANBioGRID, IntAct32296183 details
ADA21_HUMANSGTA_HUMANBioGRID, IntAct32296183 details