Entity Details

Primary name CAN11_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UMQ6
EntryNameCAN11_HUMAN
FullNameCalpain-11
TaxID9606
Evidenceevidence at transcript level
Length739
SequenceStatuscomplete
DateCreated2001-01-11
DateModified2021-06-02

Ontological Relatives

GenesCAPN11

GO terms

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GOName
GO:0001669 acrosomal vesicle
GO:0004198 calcium-dependent cysteine-type endopeptidase activity
GO:0005509 calcium ion binding
GO:0005737 cytoplasm
GO:0006508 proteolysis
GO:0008233 peptidase activity

Subcellular Location

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Subcellular Location
Cytoplasmic vesicle

Domains

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DomainNameCategoryType
IPR000169 Cysteine peptidase, cysteine active siteSiteActive site
IPR001300 Peptidase C2, calpain, catalytic domainDomainDomain
IPR002048 EF-hand domainDomainDomain
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR018247 EF-Hand 1, calcium-binding siteSiteBinding site
IPR022682 Peptidase C2, calpain, large subunit, domain IIIDomainDomain
IPR022683 Peptidase C2, calpain, domain IIIDomainDomain
IPR022684 Peptidase C2, calpain familyFamilyFamily
IPR033883 Calpain subdomain IIIDomainDomain
IPR036213 Calpain large subunit, domain III superfamilyFamilyHomologous superfamily
IPR038765 Papain-like cysteine peptidase superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
CAN11_HUMANXRCC6_HUMANBioGRID, IntAct21988832 details
CAN11_HUMANUNG_HUMANBioGRID, IntAct21988832 details
CAN11_HUMANKAP0_HUMANBioGRID, IntAct21988832 details
CAN11_HUMANAPC11_HUMANBioGRID, IntAct21988832 details