Entity Details

Primary name POLI_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UNA4
EntryNamePOLI_HUMAN
FullNameDNA polymerase iota
TaxID9606
Evidenceevidence at protein level
Length740
SequenceStatuscomplete
DateCreated2005-02-15
DateModified2021-06-02

Ontological Relatives

GenesPOLI

GO terms

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GOName
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005654 nucleoplasm
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0016607 nuclear speck
GO:0019985 translesion synthesis
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0042276 error-prone translesion synthesis
GO:0046872 metal ion binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001126 UmuC domainDomainDomain
IPR017961 DNA polymerase, Y-family, little finger domainDomainDomain
IPR036775 DNA polymerase, Y-family, little finger domain superfamilyFamilyHomologous superfamily
IPR043128 Reverse transcriptase/Diguanylate cyclase domainFamilyHomologous superfamily
IPR043502 DNA/RNA polymerase superfamilyFamilyHomologous superfamily

Diseases

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Interactions

28 interactions

InteractorPartnerSourcesPublicationsLink
POLI_HUMANRNF11_HUMANBioGRID, HPRD, MINT15231748 details
POLI_HUMANDVL2_HUMANBioGRID, HPRD, IntAct16189514 31515488 details
POLI_HUMANDAZP2_HUMANBioGRID, HPRD, IntAct16189514 19060904 details
POLI_HUMANCACO2_HUMANBioGRID, HPRD, IntAct16189514 details
POLI_HUMANUBC_HUMANBioGRID, MINT16763556 20159559 23248005 30659753 31699778 details
POLI_HUMANTRI23_HUMANBioGRID, IntAct19060904 details
POLI_HUMANTRI39_HUMANBioGRID, IntAct, MINT21516116 25416956 details
POLI_HUMANZBT44_HUMANBioGRID, IntAct25416956 details
POLI_HUMANTM239_HUMANBioGRID, IntAct25416956 details
POLI_HUMANTRAF6_HUMANBioGRID, IntAct25416956 details
POLI_HUMANMTR1B_HUMANBioGRID, IntAct26514267 details
POLI_HUMANHOME3_HUMANBioGRID, IntAct32296183 details
POLI_HUMANMFHA1_HUMANBioGRID, IntAct29513927 details
POLI_HUMANNEDD8_HUMANBioGRID, MINT30659753 details
POLI_HUMANKPCA_HUMANIntAct32814053 details
POLI_HUMAN1433G_HUMANIntAct32814053 details
POLI_HUMANSETB1_HUMANIntAct32814053 details
POLI_HUMANKAT5_HUMANIntAct32814053 details
POLI_HUMANLMO3_HUMANIntAct32814053 details
POLI_HUMANUBB_HUMANBioGRID, HPRD16763556 details
POLI_HUMANPCNA_HUMANBioGRID, HPRD11724965 15342632 16763556 18931444 23248005 26903512 details
POLI_HUMANREV1_HUMANBioGRID, HPRD15189446 19170759 30886224 details
POLI_HUMANPOLH_HUMANBioGRID, HPRD12426396 12606586 16763556 23248005 details
POLI_HUMANA4_HUMANBioGRID21832049 details
POLI_HUMANEP300_HUMANBioGRID30886224 details
POLI_HUMANRL40_HUMANHPRD16763556 details
POLI_HUMANXRCC1_HUMANBioGRID, MINT18923427 details
POLI_HUMANP53_HUMANBioGRID27407148 details