Entity Details

Primary name PLCL2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UPR0
EntryNamePLCL2_HUMAN
FullNameInactive phospholipase C-like protein 2
TaxID9606
Evidenceevidence at protein level
Length1127
SequenceStatuscomplete
DateCreated2007-05-29
DateModified2021-06-02

Ontological Relatives

GenesPLCL2

GO terms

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GOName
GO:0002322 B cell proliferation involved in immune response
GO:0002337 B-1a B cell differentiation
GO:0004435 phosphatidylinositol phospholipase C activity
GO:0005737 cytoplasm
GO:0006629 lipid metabolic process
GO:0007214 gamma-aminobutyric acid signaling pathway
GO:0032228 regulation of synaptic transmission, GABAergic
GO:0033135 regulation of peptidyl-serine phosphorylation
GO:0048015 phosphatidylinositol-mediated signaling
GO:0050811 GABA receptor binding
GO:0050859 negative regulation of B cell receptor signaling pathway
GO:0070679 inositol 1,4,5 trisphosphate binding
GO:0120163 negative regulation of cold-induced thermogenesis
GO:1900122 positive regulation of receptor binding

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000008 C2 domainDomainDomain
IPR000909 Phosphatidylinositol-specific phospholipase C, X domainDomainDomain
IPR001192 Phosphoinositide phospholipase C familyFamilyFamily
IPR001711 Phospholipase C, phosphatidylinositol-specific, Y domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR015359 Phosphoinositide-specific phospholipase C, EF-hand-like domainDomainDomain
IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamilyFamilyHomologous superfamily
IPR028382 Inactive phospholipase C-like protein 2FamilyFamily
IPR035892 C2 domain superfamilyFamilyHomologous superfamily

Diseases

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