Entity Details

Primary name NISCH_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y2I1
EntryNameNISCH_HUMAN
FullNameNischarin
TaxID9606
Evidenceevidence at protein level
Length1504
SequenceStatuscomplete
DateCreated2008-09-02
DateModified2021-06-02

Ontological Relatives

GenesNISCH

GO terms

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GOName
GO:0005178 integrin binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006006 glucose metabolic process
GO:0006915 apoptotic process
GO:0008217 regulation of blood pressure
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
GO:0016601 Rac protein signal transduction
GO:0019901 protein kinase binding
GO:0030036 actin cytoskeleton organization
GO:0030336 negative regulation of cell migration
GO:0032228 regulation of synaptic transmission, GABAergic
GO:0035091 phosphatidylinositol binding
GO:0042802 identical protein binding
GO:0043231 intracellular membrane-bounded organelle
GO:0045171 intercellular bridge
GO:0048243 norepinephrine secretion
GO:0055037 recycling endosome

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm
Early endosome
Recycling endosome

Domains

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DomainNameCategoryType
IPR001611 Leucine-rich repeatRepeatRepeat
IPR001683 Phox homologyDomainDomain
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily
IPR036871 PX domain superfamilyFamilyHomologous superfamily
IPR037904 Nischarin, PX domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00697 TizanidineDrugbanksmall molecule
DB08838 AgmatineDrugbanksmall molecule
DB09242 MoxonidineDrugbanksmall molecule

Interactions

29 interactions

InteractorPartnerSourcesPublicationsLink
NISCH_HUMANRAB9A_HUMANBioGRID, IntAct, MINT23386062 29568061 34079125 details
NISCH_HUMANPE2R4_HUMANBioGRID, MINT28298427 details
NISCH_HUMANOGT1_HUMANBioGRID32994395 details
NISCH_HUMANSCHI1_HUMANIntAct20195357 details
NISCH_HUMANRAB14_HUMANMINT23386062 details
NISCH_HUMANEEA1_HUMANMINT23386062 details
NISCH_HUMANNISCH_HUMANMINT23386062 details
NISCH_HUMANNUDC3_HUMANIntAct25036637 details
NISCH_HUMANIRS4_HUMANBioGRID, HPRD, IntAct11912194 25036637 details
NISCH_HUMANP85A_HUMANBioGRID, IntAct27173435 32203420 unassigned1312 details
NISCH_HUMANK1671_HUMANBioGRID, IntAct27173435 unassigned1312 details
NISCH_HUMANPAN2_HUMANBioGRID, IntAct27173435 unassigned1312 details
NISCH_HUMANSWAHA_HUMANIntActunassigned1312 details
NISCH_HUMANCTBP1_HUMANBioGRID, IntAct27173435 unassigned1312 details
NISCH_HUMANERF_HUMANBioGRID, IntAct27173435 unassigned1312 details
NISCH_HUMANHELZ_HUMANBioGRID, IntAct27173435 unassigned1312 details
NISCH_HUMANP121C_HUMANIntActunassigned1312 details
NISCH_HUMANPCGF3_HUMANBioGRID, IntAct27173435 unassigned1312 details
NISCH_HUMANPCGF5_HUMANBioGRID, IntAct27173435 unassigned1312 details
NISCH_HUMANMARF1_HUMANBioGRID, IntAct27173435 unassigned1312 details
NISCH_HUMANNUP50_HUMANBioGRID, IntAct27173435 unassigned1312 details
NISCH_HUMAN4ET_HUMANBioGRID, IntAct27173435 unassigned1312 details
NISCH_HUMANARI3A_HUMANBioGRID, IntAct27173435 unassigned1312 details
NISCH_HUMANCBP_HUMANBioGRID, IntAct27173435 unassigned1312 details
NISCH_HUMANIRS1_HUMANBioGRID11912194 details
NISCH_HUMANIRS2_HUMANBioGRID11912194 details
NISCH_HUMANF120C_HUMANBioGRID29395067 details
NISCH_HUMANANDR_HUMANHPRD15028622 details
NISCH_HUMANITA5_HUMANHPRD12868002 15028619 details