Entity Details

Primary name PLXD1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y4D7
EntryNamePLXD1_HUMAN
FullNamePlexin-D1
TaxID9606
Evidenceevidence at protein level
Length1925
SequenceStatuscomplete
DateCreated2004-08-31
DateModified2021-06-02

Ontological Relatives

GenesPLXND1

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001569 branching involved in blood vessel morphogenesis
GO:0001822 kidney development
GO:0002116 semaphorin receptor complex
GO:0003151 outflow tract morphogenesis
GO:0003279 cardiac septum development
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007162 negative regulation of cell adhesion
GO:0007221 positive regulation of transcription of Notch receptor target
GO:0007416 synapse assembly
GO:0008360 regulation of cell shape
GO:0017154 semaphorin receptor activity
GO:0019904 protein domain specific binding
GO:0030027 lamellipodium
GO:0030334 regulation of cell migration
GO:0031258 lamellipodium membrane
GO:0032092 positive regulation of protein binding
GO:0035904 aorta development
GO:0043087 regulation of GTPase activity
GO:0043542 endothelial cell migration
GO:0045765 regulation of angiogenesis
GO:0050772 positive regulation of axonogenesis
GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching
GO:0060976 coronary vasculature development
GO:0071526 semaphorin-plexin signaling pathway
GO:1902287 semaphorin-plexin signaling pathway involved in axon guidance

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection

Domains

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DomainNameCategoryType
IPR001627 Sema domainDomainDomain
IPR002165 Plexin repeatRepeatRepeat
IPR002909 IPT domainDomainDomain
IPR008936 Rho GTPase activation proteinFamilyHomologous superfamily
IPR013548 Plexin, cytoplasmic RasGAP domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR016201 PSI domainDomainDomain
IPR031148 Plexin familyFamilyFamily
IPR036352 Sema domain superfamilyFamilyHomologous superfamily
IPR041019 Plexin, TIG domain 1DomainDomain
IPR042719 Plexin-D1, sema domainDomainDomain

Diseases

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