Entity Details

Primary name SPEF1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y4P9
EntryNameSPEF1_HUMAN
FullNameSperm flagellar protein 1
TaxID9606
Evidenceevidence at protein level
Length236
SequenceStatuscomplete
DateCreated2002-09-19
DateModified2021-06-02

Ontological Relatives

GenesSPEF1

GO terms

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GOName
GO:0001578 microtubule bundle formation
GO:0003341 cilium movement
GO:0003779 actin binding
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0005902 microvillus
GO:0005930 axoneme
GO:0007026 negative regulation of microtubule depolymerization
GO:0008017 microtubule binding
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016477 cell migration
GO:0030027 lamellipodium
GO:0030032 lamellipodium assembly
GO:0030175 filopodium
GO:0046847 filopodium assembly
GO:0051493 regulation of cytoskeleton organization
GO:0060548 negative regulation of cell death
GO:0097542 ciliary tip
GO:0097729 9+2 motile cilium
GO:1904158 axonemal central apparatus assembly
GO:1990716 axonemal central apparatus
GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway

Subcellular Location

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Subcellular Location
Apical cell membrane
Basolateral cell membrane
Cell projection
Cytoplasm

Domains

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DomainNameCategoryType
IPR001715 Calponin homology domainDomainDomain
IPR010441 CH-like domain in sperm proteinDomainDomain
IPR036872 CH domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
SPEF1_HUMANZBED1_HUMANBioGRID, HPRD, IntAct16189514 details
SPEF1_HUMANPKHF2_HUMANBioGRID, HPRD, IntAct16189514 32296183 details
SPEF1_HUMANK1C40_HUMANBioGRID, IntAct25416956 details
SPEF1_HUMANCRTP1_HUMANBioGRID, IntAct32296183 details
SPEF1_HUMANKR132_HUMANBioGRID, IntAct32296183 details