Entity Details

Primary name SNX5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y5X3
EntryNameSNX5_HUMAN
FullNameSorting nexin-5
TaxID9606
Evidenceevidence at protein level
Length404
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesSNX5

GO terms

Show/Hide Table
GOName
GO:0001726 ruffle
GO:0001891 phagocytic cup
GO:0005768 endosome
GO:0005829 cytosol
GO:0005903 brush border
GO:0006886 intracellular protein transport
GO:0006907 pinocytosis
GO:0007174 epidermal growth factor catabolic process
GO:0010314 phosphatidylinositol-5-phosphate binding
GO:0016241 regulation of macroautophagy
GO:0030659 cytoplasmic vesicle membrane
GO:0030904 retromer complex
GO:0030905 retromer, tubulation complex
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0031313 extrinsic component of endosome membrane
GO:0031748 D1 dopamine receptor binding
GO:0031901 early endosome membrane
GO:0034452 dynactin binding
GO:0035091 phosphatidylinositol binding
GO:0035815 positive regulation of renal sodium excretion
GO:0042147 retrograde transport, endosome to Golgi
GO:0043231 intracellular membrane-bounded organelle
GO:0045296 cadherin binding
GO:0045776 negative regulation of blood pressure
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046628 positive regulation of insulin receptor signaling pathway
GO:0048471 perinuclear region of cytoplasm
GO:0070273 phosphatidylinositol-4-phosphate binding
GO:0070685 macropinocytic cup
GO:0080025 phosphatidylinositol-3,5-bisphosphate binding
GO:0097422 tubular endosome

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane
Cell projection
Cytoplasm
Cytoplasmic vesicle membrane
Early endosome
Early endosome membrane
Endosome

Domains

Show/Hide Table
DomainNameCategoryType
IPR001683 Phox homologyDomainDomain
IPR014637 Sorting nexin-5/6/32FamilyFamily
IPR015404 Sorting nexin Vps5-like, C-terminalDomainDomain
IPR027267 AH/BAR domain superfamilyFamilyHomologous superfamily
IPR028654 Sorting nexin-5FamilyFamily
IPR036871 PX domain superfamilyFamilyHomologous superfamily
IPR042135 SNX5, PX domainDomainDomain

Diseases

Show/Hide Table