Entity Details

Primary name TLL2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y6L7
EntryNameTLL2_HUMAN
FullNameTolloid-like protein 2
TaxID9606
Evidenceevidence at protein level
Length1015
SequenceStatuscomplete
DateCreated2006-02-07
DateModified2021-06-02

Ontological Relatives

GenesTLL2

GO terms

Show/Hide Table
GOName
GO:0004222 metalloendopeptidase activity
GO:0005509 calcium ion binding
GO:0005576 extracellular region
GO:0007275 multicellular organism development
GO:0008270 zinc ion binding
GO:0022617 extracellular matrix disassembly
GO:0030154 cell differentiation
GO:0030199 collagen fibril organization
GO:0048632 negative regulation of skeletal muscle tissue growth

Subcellular Location

Show/Hide Table
Subcellular Location
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000742 EGF-like domainDomainDomain
IPR000859 CUB domainDomainDomain
IPR001506 Peptidase M12ADomainDomain
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR006026 Peptidase, metallopeptidaseDomainDomain
IPR015446 Bone morphogenetic protein 1/tolloid-like proteinFamilyFamily
IPR018097 EGF-like calcium-binding, conserved siteSiteConserved site
IPR024079 Metallopeptidase, catalytic domain superfamilyFamilyHomologous superfamily
IPR034036 Tolloid/BMP1 peptidase domainDomainDomain
IPR035914 Spermadhesin, CUB domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB01989 Methyl N-{[(1R)-1-({1-[(benzyloxy)carbonyl]-L-prolyl-6-ammonio-L-norleucyl}amino)-2-phenylethyl](hydroxy)phosphoryl}-L-alanyl-L-prolinateDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink