Entity Details

Primary name NPHN_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60500
EntryNameNPHN_HUMAN
FullNameNephrin
TaxID9606
Evidenceevidence at protein level
Length1241
SequenceStatuscomplete
DateCreated2002-04-16
DateModified2021-06-02

Ontological Relatives

GenesNPHS1

GO terms

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GOName
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0005925 focal adhesion
GO:0007155 cell adhesion
GO:0007254 JNK cascade
GO:0007519 skeletal muscle tissue development
GO:0007520 myoblast fusion
GO:0007588 excretion
GO:0017022 myosin binding
GO:0030838 positive regulation of actin filament polymerization
GO:0032836 glomerular basement membrane development
GO:0035418 protein localization to synapse
GO:0036057 slit diaphragm
GO:0042995 cell projection
GO:0044062 regulation of excretion
GO:0050839 cell adhesion molecule binding
GO:0070062 extracellular exosome
GO:0072015 glomerular visceral epithelial cell development
GO:0098609 cell-cell adhesion

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013098 Immunoglobulin I-setDomainDomain
IPR013162 CD80-like, immunoglobulin C2-setDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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