Entity Details

Primary name UGDH_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60701
EntryNameUGDH_HUMAN
FullNameUDP-glucose 6-dehydrogenase
TaxID9606
Evidenceevidence at protein level
Length494
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesUGDH

GO terms

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GOName
GO:0001702 gastrulation with mouth forming second
GO:0003979 UDP-glucose 6-dehydrogenase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005975 carbohydrate metabolic process
GO:0006024 glycosaminoglycan biosynthetic process
GO:0006065 UDP-glucuronate biosynthetic process
GO:0015012 heparan sulfate proteoglycan biosynthetic process
GO:0030206 chondroitin sulfate biosynthetic process
GO:0034214 protein hexamerization
GO:0042802 identical protein binding
GO:0048666 neuron development
GO:0051287 NAD binding
GO:0070062 extracellular exosome

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminalDomainDomain
IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamilyFamilyHomologous superfamily
IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisationDomainDomain
IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminalDomainDomain
IPR017476 UDP-glucose/GDP-mannose dehydrogenaseFamilyFamily
IPR028356 UDP-glucose 6-dehydrogenase, eukaryotic typeFamilyFamily
IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamilyFamilyHomologous superfamily
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule
DB09130 CopperDrugbanksmall molecule