Entity Details

Primary name NFAT5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO94916
EntryNameNFAT5_HUMAN
FullNameNuclear factor of activated T-cells 5
TaxID9606
Evidenceevidence at protein level
Length1531
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesNFAT5

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006366 transcription by RNA polymerase II
GO:0006970 response to osmotic stress
GO:0007165 signal transduction
GO:0007588 excretion
GO:0008134 transcription factor binding
GO:0010628 positive regulation of gene expression
GO:0033173 calcineurin-NFAT signaling cascade
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0070884 regulation of calcineurin-NFAT signaling cascade
GO:0071345 cellular response to cytokine stimulus
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR002909 IPT domainDomainDomain
IPR008366 Nuclear factor of activated T cells (NFAT)FamilyFamily
IPR008967 p53-like transcription factor, DNA-bindingFamilyHomologous superfamily
IPR011539 Rel homology domain (RHD), DNA-binding domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR015646 Nuclear factor of activated T-cells 5FamilyFamily
IPR032397 Rel homology dimerisation domainDomainDomain
IPR037059 Rel homology domain (RHD), DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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