Entity Details

Primary name PRL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP01236
EntryNamePRL_HUMAN
FullNameProlactin
TaxID9606
Evidenceevidence at protein level
Length227
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesPRL

GO terms

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GOName
GO:0001937 negative regulation of endothelial cell proliferation
GO:0005148 prolactin receptor binding
GO:0005179 hormone activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0007166 cell surface receptor signaling pathway
GO:0007565 female pregnancy
GO:0007595 lactation
GO:0008284 positive regulation of cell population proliferation
GO:0016525 negative regulation of angiogenesis
GO:0030879 mammary gland development
GO:0031667 response to nutrient levels
GO:0031904 endosome lumen
GO:0040014 regulation of multicellular organism growth
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
GO:0060397 growth hormone receptor signaling pathway via JAK-STAT
GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II
GO:1903489 positive regulation of lactation
GO:1990000 amyloid fibril formation

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001400 Somatotropin/prolactinFamilyFamily
IPR009079 Four-helical cytokine-like, coreFamilyHomologous superfamily
IPR018116 Somatotropin hormone, conserved siteSiteConserved site

Diseases

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