Entity Details

Primary name CD1A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP06126
EntryNameCD1A_HUMAN
FullNameT-cell surface glycoprotein CD1a
TaxID9606
Evidenceevidence at protein level
Length327
SequenceStatuscomplete
DateCreated1988-01-01
DateModified2021-06-02

Ontological Relatives

GenesCD1A

GO terms

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GOName
GO:0001916 positive regulation of T cell mediated cytotoxicity
GO:0002250 adaptive immune response
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006955 immune response
GO:0009897 external side of plasma membrane
GO:0010008 endosome membrane
GO:0030883 endogenous lipid antigen binding
GO:0030884 exogenous lipid antigen binding
GO:0045121 membrane raft
GO:0048006 antigen processing and presentation, endogenous lipid antigen via MHC class Ib
GO:0048007 antigen processing and presentation, exogenous lipid antigen via MHC class Ib
GO:0050776 regulation of immune response
GO:0071723 lipopeptide binding

Subcellular Location

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Subcellular Location
Cell membrane
Endosome membrane
Membrane raft

Domains

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DomainNameCategoryType
IPR003597 Immunoglobulin C1-setDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR011161 MHC class I-like antigen recognition-likeDomainDomain
IPR011162 MHC classes I/II-like antigen recognition proteinFamilyHomologous superfamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR037055 MHC class I-like antigen recognition-like superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00098 Antithymocyte immunoglobulin (rabbit)Drugbankbiotech

Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
CD1A_HUMANB2MG_HUMANHPRD, IntAct12833155 15723809 details
CD1A_HUMANDGAT1_HUMANBioGRID, IntAct21988832 details
CD1A_HUMANKCTD5_HUMANBioGRID, IntAct21988832 details
CD1A_HUMANUBTD1_HUMANBioGRID, IntAct21988832 details