Entity Details

Primary name ATPB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP06576
EntryNameATPB_HUMAN
FullNameATP synthase subunit beta, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length529
SequenceStatuscomplete
DateCreated1988-01-01
DateModified2021-06-02

Ontological Relatives

GenesATP5F1B

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001649 osteoblast differentiation
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005753 mitochondrial proton-transporting ATP synthase complex
GO:0005754 mitochondrial proton-transporting ATP synthase, catalytic core
GO:0005759 mitochondrial matrix
GO:0005886 plasma membrane
GO:0006091 generation of precursor metabolites and energy
GO:0006629 lipid metabolic process
GO:0006754 ATP biosynthetic process
GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration
GO:0007005 mitochondrion organization
GO:0009986 cell surface
GO:0016020 membrane
GO:0031966 mitochondrial membrane
GO:0042288 MHC class I protein binding
GO:0042407 cristae formation
GO:0042645 mitochondrial nucleoid
GO:0042776 mitochondrial ATP synthesis coupled proton transport
GO:0043532 angiostatin binding
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0045259 proton-transporting ATP synthase complex
GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
GO:0046961 proton-transporting ATPase activity, rotational mechanism
GO:0051453 regulation of intracellular pH
GO:0070062 extracellular exosome
GO:0098761 cellular response to interleukin-7
GO:1902600 proton transmembrane transport

Subcellular Location

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Subcellular Location
Mitochondrion inner membrane

Domains

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DomainNameCategoryType
IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domainDomainDomain
IPR003593 AAA+ ATPase domainDomainDomain
IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domainDomainDomain
IPR005722 ATP synthase, F1 complex, beta subunitFamilyFamily
IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active siteSiteActive site
IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminalFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04216 QuercetinDrugbanksmall molecule
DB07384 1-ACETYL-2-CARBOXYPIPERIDINEDrugbanksmall molecule
DB07394 AUROVERTIN BDrugbanksmall molecule
DB08399 PiceatannolDrugbanksmall molecule
DB08629 N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINEDrugbanksmall molecule
DB08949 Inositol nicotinateDrugbanksmall molecule
DB12695 Phenethyl IsothiocyanateDrugbanksmall molecule

Interactions

44 interactions

InteractorPartnerSourcesPublicationsLink
ATPB_HUMANPSME3_HUMANBioGRID, HPRD, IntAct16169070 details
ATPB_HUMANATPF1_HUMANBioGRID, HPRD, IntAct11410595 12206899 28514442 details
ATPB_HUMANTRI63_HUMANBioGRID, MINT18157088 23695782 details
ATPB_HUMANSMUF2_HUMANMINT18157088 details
ATPB_HUMANANXA7_HUMANBioGRID, MINT21900206 details
ATPB_HUMANCDK4_HUMANBioGRID, MINT21900206 details
ATPB_HUMANCDN1A_HUMANBioGRID, MINT21900206 details
ATPB_HUMANGRB7_HUMANBioGRID, MINT21900206 details
ATPB_HUMANHMOX2_HUMANBioGRID, MINT21900206 31536960 details
ATPB_HUMANPIN1_HUMANBioGRID, MINT21900206 details
ATPB_HUMANRPP14_HUMANBioGRID, MINT21900206 details
ATPB_HUMANSMN_HUMANBioGRID, MINT21900206 details
ATPB_HUMANKITH_HUMANBioGRID, MINT21900206 details
ATPB_HUMANATPF2_HUMANBioGRID, HPRD, IntAct11410595 21516116 25416956 29892012 31515488 32296183 details
ATPB_HUMANBYST_HUMANBioGRID, IntAct32296183 details
ATPB_HUMANATPA_HUMANBioGRID, IntAct22939629 25416956 26344197 27499296 28514442 30021884 31536960 details
ATPB_HUMANATP5J_HUMANBioGRID, IntAct16230521 28514442 details
ATPB_HUMANLNX2_HUMANBioGRID, IntAct21516116 29892012 31515488 details
ATPB_HUMANATX1_HUMANIntAct32814053 details
ATPB_HUMANFANCA_HUMANBioGRID14499622 details
ATPB_HUMANTERT_HUMANBioGRID23741361 details
ATPB_HUMANTRI55_HUMANBioGRID18157088 details
ATPB_HUMANOGT1_HUMANBioGRID32994395 details
ATPB_HUMANNEMO_HUMANIntAct14743216 details
ATPB_HUMAN1433G_HUMANHPRD, MINT15324660 details
ATPB_HUMAN1433Z_HUMANMINT15161933 20618440 details
ATPB_HUMANFIS1_HUMANBioGRID, MINT24176932 32877691 details
ATPB_HUMANATPG_HUMANBioGRID, HPRD, IntAct22939629 26344197 28514442 31536960 8065448 details
ATPB_HUMANPMS2L_HUMANIntAct30021884 details
ATPB_HUMANDISC1_HUMANIntAct31413325 details
ATPB_HUMANPSMD4_HUMANBioGRID12601813 details
ATPB_HUMAN1433T_HUMANBioGRID20618440 details
ATPB_HUMANHDAC5_HUMANBioGRID21081666 details
ATPB_HUMANMK03_HUMANBioGRID19847302 details
ATPB_HUMANISG15_HUMANBioGRID16009940 33024031 details
ATPB_HUMANCAH9_HUMANBioGRID23181366 details
ATPB_HUMANGRSF1_HUMANBioGRID23473034 details
ATPB_HUMANSPRTN_HUMANBioGRID23254330 details
ATPB_HUMANADX_HUMANBioGRID20547883 details
ATPB_HUMANPPT1_HUMANBioGRID25865307 26217791 details
ATPB_HUMANCETN3_HUMANBioGRID30251372 details
ATPB_HUMANSUMO4_HUMANHPRD16236267 details
ATPB_HUMANPLMN_HUMANHPRD10077593 details
ATPB_HUMANAPOA1_HUMANHPRD2687158 details