Entity Details

Primary name CEAM5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP06731
EntryNameCEAM5_HUMAN
FullNameCarcinoembryonic antigen-related cell adhesion molecule 5
TaxID9606
Evidenceevidence at protein level
Length702
SequenceStatuscomplete
DateCreated1988-01-01
DateModified2021-06-02

Ontological Relatives

GenesCEACAM5

GO terms

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GOName
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006915 apoptotic process
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0009986 cell surface
GO:0010832 negative regulation of myotube differentiation
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0031225 anchored component of membrane
GO:0034109 homotypic cell-cell adhesion
GO:0034235 GPI anchor binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043066 negative regulation of apoptotic process
GO:0050900 leukocyte migration
GO:0070062 extracellular exosome
GO:0071575 integral component of external side of plasma membrane
GO:2000811 negative regulation of anoikis

Subcellular Location

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Subcellular Location
Apical cell membrane
Cell membrane
Cell surface

Domains

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DomainNameCategoryType
IPR003598 Immunoglobulin subtype 2DomainDomain
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB05097 LabetuzumabDrugbankbiotech
DB08217 S-[(1-Hydroxy-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioateDrugbanksmall molecule