Entity Details

Primary name CENPB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP07199
EntryNameCENPB_HUMAN
FullNameMajor centromere autoantigen B
TaxID9606
Evidenceevidence at protein level
Length599
SequenceStatuscomplete
DateCreated1988-04-01
DateModified2021-06-02

Ontological Relatives

GenesCENPB

GO terms

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GOName
GO:0000775 chromosome, centromeric region
GO:0000779 condensed chromosome, centromeric region
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003696 satellite DNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005721 pericentric heterochromatin
GO:0016604 nuclear body
GO:0019237 centromeric DNA binding
GO:0043565 sequence-specific DNA binding

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR004875 DDE superfamily endonuclease domainDomainDomain
IPR006600 HTH CenpB-type DNA-binding domainDomainDomain
IPR007889 DNA binding HTH domain, Psq-typeDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR015115 Centromere protein CENP-B, C-terminal domainDomainDomain
IPR033062 Major centromere autoantigen BFamilyFamily
IPR034882 CENP-B, dimerisation domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

29 interactions

InteractorPartnerSourcesPublicationsLink
CENPB_HUMANGFI1B_HUMANBioGRID, HPRD, IntAct16713569 details
CENPB_HUMANGCR_HUMANBioGRID, IntAct20195357 details
CENPB_HUMANANXA7_HUMANBioGRID, MINT21900206 details
CENPB_HUMANCDN1A_HUMANBioGRID, MINT21900206 details
CENPB_HUMANCSK2B_HUMANBioGRID, MINT21900206 details
CENPB_HUMANGA45A_HUMANBioGRID, MINT21900206 details
CENPB_HUMANGSK3B_HUMANBioGRID, MINT21900206 details
CENPB_HUMANPIN1_HUMANBioGRID, MINT21900206 details
CENPB_HUMANKS6A6_HUMANBioGRID, MINT21900206 details
CENPB_HUMANSMN_HUMANBioGRID, MINT21900206 details
CENPB_HUMANTKN1_HUMANBioGRID, MINT21900206 details
CENPB_HUMANKITH_HUMANBioGRID, MINT21900206 details
CENPB_HUMANSH23A_HUMANBioGRID, IntAct25814554 details
CENPB_HUMANADRB2_HUMANBioGRID, MINT28298427 details
CENPB_HUMANHAND2_HUMANBioGRID, HPRD11812799 details
CENPB_HUMANA4_HUMANBioGRID21832049 details
CENPB_HUMANFBX25_HUMANBioGRID23940030 details
CENPB_HUMANCENPW_HUMANBioGRID25775162 details
CENPB_HUMANNUF2_HUMANUniProt11266451 details
CENPB_HUMANNDC80_HUMANUniProt11266451 details
CENPB_HUMANOPTN_HUMANIntAct20195357 details
CENPB_HUMANNR4A1_HUMANIntAct20195357 details
CENPB_HUMANETS1_HUMANIntAct20195357 details
CENPB_HUMANMOV10_HUMANBioGRID, IntAct27173435 unassigned1312 details
CENPB_HUMANPARP1_HUMANBioGRID, HPRD12011073 details
CENPB_HUMANCENPA_HUMANBioGRID15009096 16622419 details
CENPB_HUMANDAXX_HUMANBioGRID29273057 details
CENPB_HUMANCENPB_HUMANHPRD14522975 details
CENPB_HUMANPARP2_HUMANHPRD12217960 details