Entity Details

Primary name WNT2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP09544
EntryNameWNT2_HUMAN
FullNameProtein Wnt-2
TaxID9606
Evidenceevidence at transcript level
Length360
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesWNT2

GO terms

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GOName
GO:0001938 positive regulation of endothelial cell proliferation
GO:0002053 positive regulation of mesenchymal cell proliferation
GO:0002088 lens development in camera-type eye
GO:0005109 frizzled binding
GO:0005125 cytokine activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0007267 cell-cell signaling
GO:0008284 positive regulation of cell population proliferation
GO:0016055 Wnt signaling pathway
GO:0022008 neurogenesis
GO:0030182 neuron differentiation
GO:0030324 lung development
GO:0031232 extrinsic component of external side of plasma membrane
GO:0033278 cell proliferation in midbrain
GO:0045165 cell fate commitment
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048018 receptor ligand activity
GO:0048146 positive regulation of fibroblast proliferation
GO:0050769 positive regulation of neurogenesis
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0055009 atrial cardiac muscle tissue morphogenesis
GO:0060045 positive regulation of cardiac muscle cell proliferation
GO:0060070 canonical Wnt signaling pathway
GO:0060317 cardiac epithelial to mesenchymal transition
GO:0060492 lung induction
GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis
GO:0060716 labyrinthine layer blood vessel development
GO:0061072 iris morphogenesis
GO:0061180 mammary gland epithelium development
GO:0062023 collagen-containing extracellular matrix
GO:0071300 cellular response to retinoic acid
GO:0071560 cellular response to transforming growth factor beta stimulus
GO:1904948 midbrain dopaminergic neuron differentiation
GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation
GO:1990909 Wnt signalosome

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR005817 WntFamilyFamily
IPR009140 Wnt-2 proteinFamilyFamily
IPR018161 Wnt protein, conserved siteSiteConserved site
IPR043158 Wnt, C-terminal domainFamilyHomologous superfamily

Diseases

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