Entity Details

Primary name GLI2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP10070
EntryNameGLI2_HUMAN
FullNameZinc finger protein GLI2
TaxID9606
Evidenceevidence at protein level
Length1586
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesGLI2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001501 skeletal system development
GO:0001649 osteoblast differentiation
GO:0001701 in utero embryonic development
GO:0001822 kidney development
GO:0002062 chondrocyte differentiation
GO:0002076 osteoblast development
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0005929 cilium
GO:0005930 axoneme
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007224 smoothened signaling pathway
GO:0007389 pattern specification process
GO:0007411 axon guidance
GO:0007418 ventral midline development
GO:0007442 hindgut morphogenesis
GO:0007507 heart development
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0009913 epidermal cell differentiation
GO:0009952 anterior/posterior pattern specification
GO:0009954 proximal/distal pattern formation
GO:0016020 membrane
GO:0016607 nuclear speck
GO:0021508 floor plate formation
GO:0021513 spinal cord dorsal/ventral patterning
GO:0021517 ventral spinal cord development
GO:0021696 cerebellar cortex morphogenesis
GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification
GO:0021776 smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
GO:0021965 spinal cord ventral commissure morphogenesis
GO:0021983 pituitary gland development
GO:0030324 lung development
GO:0030879 mammary gland development
GO:0030902 hindbrain development
GO:0031069 hair follicle morphogenesis
GO:0031514 motile cilium
GO:0032331 negative regulation of chondrocyte differentiation
GO:0033089 positive regulation of T cell differentiation in thymus
GO:0035295 tube development
GO:0042475 odontogenesis of dentin-containing tooth
GO:0042733 embryonic digit morphogenesis
GO:0043066 negative regulation of apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0045666 positive regulation of neuron differentiation
GO:0045740 positive regulation of DNA replication
GO:0045879 negative regulation of smoothened signaling pathway
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048566 embryonic digestive tract development
GO:0048589 developmental growth
GO:0048666 neuron development
GO:0048754 branching morphogenesis of an epithelial tube
GO:0060032 notochord regression
GO:0060513 prostatic bud formation
GO:0060603 mammary gland duct morphogenesis
GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning
GO:0071407 cellular response to organic cyclic compound
GO:0090103 cochlea morphogenesis
GO:0097542 ciliary tip
GO:0097546 ciliary base
GO:0098586 cellular response to virus
GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
GO:1990837 sequence-specific double-stranded DNA binding
GO:1990841 promoter-specific chromatin binding

Subcellular Location

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Subcellular Location
Cell projection
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily
IPR043359 C2H2-type zinc-finger protein GLI-likeFamilyFamily

Diseases

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