Entity Details

Primary name PRPS2_HUMAN
Entity type UniProt
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Details

AccessionP11908
EntryNamePRPS2_HUMAN
FullNameRibose-phosphate pyrophosphokinase 2
TaxID9606
Evidenceevidence at protein level
Length318
SequenceStatuscomplete
DateCreated1989-10-01
DateModified2021-06-02

Ontological Relatives

GenesPRPS2

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0002189 ribose phosphate diphosphokinase complex
GO:0004749 ribose phosphate diphosphokinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006164 purine nucleotide biosynthetic process
GO:0006167 AMP biosynthetic process
GO:0009116 nucleoside metabolic process
GO:0016208 AMP binding
GO:0016301 kinase activity
GO:0019003 GDP binding
GO:0030246 carbohydrate binding
GO:0031100 animal organ regeneration
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043531 ADP binding

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000836 Phosphoribosyltransferase domainDomainDomain
IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved siteSiteConserved site
IPR005946 Ribose-phosphate pyrophosphokinaseFamilyFamily
IPR029057 Phosphoribosyltransferase-likeFamilyHomologous superfamily
IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domainDomainDomain
IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-typeFamilyFamily

Diseases

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