Entity Details

Primary name ANPRC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP17342
EntryNameANPRC_HUMAN
FullNameAtrial natriuretic peptide receptor 3
TaxID9606
Evidenceevidence at protein level
Length541
SequenceStatuscomplete
DateCreated1990-08-01
DateModified2021-06-02

Ontological Relatives

GenesNPR3

GO terms

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GOName
GO:0001501 skeletal system development
GO:0002158 osteoclast proliferation
GO:0005887 integral component of plasma membrane
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007194 negative regulation of adenylate cyclase activity
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0008217 regulation of blood pressure
GO:0008528 G protein-coupled peptide receptor activity
GO:0016941 natriuretic peptide receptor activity
GO:0017046 peptide hormone binding
GO:0030157 pancreatic juice secretion
GO:0031404 chloride ion binding
GO:0032991 protein-containing complex
GO:0033688 regulation of osteoblast proliferation
GO:0035810 positive regulation of urine volume
GO:0042277 peptide binding
GO:0042562 hormone binding
GO:0042803 protein homodimerization activity
GO:0048015 phosphatidylinositol-mediated signaling
GO:0048662 negative regulation of smooth muscle cell proliferation
GO:0051000 positive regulation of nitric-oxide synthase activity
GO:0070062 extracellular exosome
GO:0120163 negative regulation of cold-induced thermogenesis

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR001170 Adenylyl cyclase class-4/guanylyl cyclaseFamilyFamily
IPR001828 Receptor, ligand binding regionDomainDomain
IPR028082 Periplasmic binding protein-like IFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04899 NesiritideDrugbankbiotech