Entity Details

Primary name SCF_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP21583
EntryNameSCF_HUMAN
FullNameKit ligand
TaxID9606
Evidenceevidence at protein level
Length273
SequenceStatuscomplete
DateCreated1991-05-01
DateModified2021-06-02

Ontological Relatives

GenesKITLG

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001541 ovarian follicle development
GO:0001755 neural crest cell migration
GO:0002687 positive regulation of leukocyte migration
GO:0002763 positive regulation of myeloid leukocyte differentiation
GO:0005125 cytokine activity
GO:0005173 stem cell factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0007155 cell adhesion
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0008584 male gonad development
GO:0016021 integral component of membrane
GO:0030027 lamellipodium
GO:0030175 filopodium
GO:0033026 negative regulation of mast cell apoptotic process
GO:0035162 embryonic hemopoiesis
GO:0035234 ectopic germ cell programmed cell death
GO:0043406 positive regulation of MAP kinase activity
GO:0045636 positive regulation of melanocyte differentiation
GO:0046579 positive regulation of Ras protein signal transduction
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0051897 positive regulation of protein kinase B signaling
GO:0070668 positive regulation of mast cell proliferation
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:1901534 positive regulation of hematopoietic progenitor cell differentiation
GO:1902035 positive regulation of hematopoietic stem cell proliferation

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Cytoplasm
Secreted

Domains

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DomainNameCategoryType
IPR003452 Stem cell factorFamilyFamily
IPR009079 Four-helical cytokine-like, coreFamilyHomologous superfamily

Diseases

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