Entity Details

Primary name SDHB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP21912
EntryNameSDHB_HUMAN
FullNameSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length280
SequenceStatuscomplete
DateCreated1991-05-01
DateModified2021-06-02

Ontological Relatives

GenesSDHB

GO terms

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GOName
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)
GO:0005886 plasma membrane
GO:0006099 tricarboxylic acid cycle
GO:0006105 succinate metabolic process
GO:0008177 succinate dehydrogenase (ubiquinone) activity
GO:0009055 electron transfer activity
GO:0009060 aerobic respiration
GO:0022904 respiratory electron transport chain
GO:0031966 mitochondrial membrane
GO:0046872 metal ion binding
GO:0048039 ubiquinone binding
GO:0051537 2 iron, 2 sulfur cluster binding
GO:0051538 3 iron, 4 sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding

Subcellular Location

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Subcellular Location
Mitochondrion inner membrane

Domains

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DomainNameCategoryType
IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domainDomainDomain
IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur proteinFamilyFamily
IPR006058 2Fe-2S ferredoxin, iron-sulphur binding siteSiteBinding site
IPR009051 Alpha-helical ferredoxinFamilyHomologous superfamily
IPR012675 Beta-grasp domain superfamilyFamilyHomologous superfamily
IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domainDomainDomain
IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved siteSiteConserved site
IPR025192 Succinate dehydogenase/fumarate reductase N-terminalDomainDomain
IPR036010 2Fe-2S ferredoxin-like superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04141 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-TriolDrugbanksmall molecule
DB08689 Ubiquinone Q1Drugbanksmall molecule